Torrelo Antonio, Fernandez-Crehuet Pablo, Del Prado Elena, Martes Pilar, Hernández-Martín Angela, De Diego Verónica, Carapeto Francisco
Department of Dermatology, Hospital del Nino Jesus, Madrid, Spain.
Pediatr Dermatol. 2010 Mar-Apr;27(2):199-200. doi: 10.1111/j.1525-1470.2010.01098.x.
Patau syndrome is a chromosomal disorder associated with multiple malformations caused by inheritance of an extra chromosome (trisomy 13). Some skin defects have been reported in patients with Patau syndrome, such as scalp defects, glabellar stains, deep palmar creases, rocker-bottom feet, convex soles, hyperconvextity of the nails, and multiple hemangiomas. To our knowledge, widespread comedonal and cystic acne have not been previously reported in Patau syndrome.
帕陶综合征是一种染色体疾病，与因额外染色体（13三体）遗传导致的多种畸形有关。有报道称帕陶综合征患者存在一些皮肤缺陷，如头皮缺陷、眉间色斑、手掌深横纹、摇椅底足、足底凸起、指甲高度弯曲以及多发血管瘤。据我们所知，此前尚未有帕陶综合征患者出现广泛的粉刺性和囊性痤疮的报道。
