Kolling Institute, University of Sydney, New South Wales, Australia.
Am J Obstet Gynecol. 2010 Sep;203(3):215.e1-5. doi: 10.1016/j.ajog.2010.04.020.
To examine seasonality of pregnancy hypertension rates, and whether they related to sunlight levels around conception.
Data were obtained for 424,732 singleton pregnancies conceived from 2001 through 2005 in Australia. We analyzed monthly rates of pregnancy hypertension and preeclampsia in relation to monthly solar radiation.
Pregnancy hypertension rates, by month of conception, were lowest in autumn (7.3%) and highest in spring (8.9%). Higher sunlight intensity before delivery, but not around conception, was associated with decreased pregnancy hypertension (r = -0.67). Increased sunlight around conception may correlate with decreased rates of early-onset preeclampsia (r = -0.51; P = .09).
The correlation between sunlight after conception and pregnancy hypertension was opposite to that hypothesized; however, sunlight levels before delivery did correlate with lower hypertension rates. For sunlight or ambient temperature to explain seasonal variation, the plausible exposure window is the period before delivery, but this may not apply to early-onset preeclampsia.
研究妊娠高血压发生率的季节性变化，以及它们与受孕前后阳光水平的关系。
本研究的数据来自澳大利亚 2001 年至 2005 年间的 424732 例单胎妊娠。我们分析了妊娠高血压和子痫前期的月发生率与每月太阳辐射的关系。
按受孕月份计算，妊娠高血压发生率在秋季（7.3%）最低，春季（8.9%）最高。分娩前光照强度较高与妊娠高血压降低有关（r=-0.67）。受孕前后光照增加可能与早发型子痫前期发生率降低相关（r=-0.51；P=0.09）。
受孕后光照与妊娠高血压之间的相关性与假设相反；然而，分娩前的光照水平确实与较低的高血压发生率相关。要使阳光或环境温度能够解释季节性变化，合理的暴露窗口期是分娩前，但这可能不适用于早发型子痫前期。
