Freeman D E, Spencer P A
Department of Clinical Studies, New Bolton Center, George D. Widener Hospital for Large Animals, University of Pennsylvania, Kennett Square 19348.
Am J Vet Res. 1991 Apr;52(4):637-9.
Age, breed, and gender distributions of 168 horses with umbilical hernia treated at the University of Pennsylvania School of Veterinary Medicine were analyzed to determine risk factors for this disease. For the 3 breeds that constituted the largest proportion of hospital and case populations, Thoroughbred, Standardbred, and Quarter Horse, the overall ratio of females to males was 1.63. In a hospital population of the same age group, 0 to 48 months, the female to male ratio was 0.93. Compared with males, females were at significantly higher risk for umbilical hernia after adjustment for breed and age (odds ratio, 2.01; 99% confidence interval, 1.31 to 3.10; P = 0.00002). Of the 2 major breeds, Thoroughbreds were at greater risk than Standardbreds for umbilical hernia, after adjustment for gender and age (odds ratio, 1.80; 99% confidence interval, 1.10 to 2.95; P = 0.0020). The results provide information about a common congenital defect in horses that can be used for future genetic research.
对宾夕法尼亚大学兽医学院治疗的168例脐疝马匹的年龄、品种和性别分布进行了分析，以确定该疾病的风险因素。在构成医院病例群体最大比例的3个品种中，即纯种马、标准赛马和夸特马，雌性与雄性的总体比例为1.63。在同一年龄组（0至48个月）的医院病例群体中，雌性与雄性的比例为0.93。在对品种和年龄进行调整后，与雄性相比，雌性患脐疝的风险显著更高（优势比为2.01；99%置信区间为1.31至3.10；P = 0.00002）。在对性别和年龄进行调整后，在2个主要品种中，纯种马患脐疝的风险高于标准赛马（优势比为1.80；99%置信区间为1.10至2.95；P = 0.0020）。这些结果提供了有关马匹常见先天性缺陷的信息，可用于未来的基因研究。
