Furutani M, Shimada Y, Inoue K, Tobe T
First Dept. of Surgery, Faculty of Medicine, Kyoto University.
Gan To Kagaku Ryoho. 1991 Jun;18(7):1187-90.
A 49-year-old man with liver metastasis from rectal cancer was treated with cisplatin (CDDP) alone. Cisplatin was administered intravenously 3 times at a dose of 50 mg (31 mg/m2). He achieved an excellent PR (94% decrease) as determined by CT scanning, and plasma CEA level decreased from 37 to 2.2 ng/ml. The side effects were nausea, vomiting, and reflux esophagitis, but neither leucopenia nor renal dysfunction was observed. As a result, a radical operation could be undertaken.