Department of Anesthesiology and Intensive Care II, Leipzig Heart Center, University of Leipzig, Leipzig, Germany.
J Cardiothorac Vasc Anesth. 2010 Oct;24(5):785-9. doi: 10.1053/j.jvca.2010.03.018. Epub 2010 May 26.
To determine the occurrence of intraoperative awareness with recall in cardiac surgery patients undergoing fast-track anesthetic management in a direct-admission postanesthetic care unit.
Prospective.
University-affiliated heart center.
Five hundred thirty-four patients undergoing fast-track anesthesia.
Using a structured interview process as part of the quality-assurance program.
All fast-track patients during an 8-month period were entered into the study at a university hospital. Each patient was interviewed by research staff with the same standard set of questions within the first 24 hours of surgery. Follow-up interviews were performed on day 3 or 4 as well as on day 6 or 7 postsurgery. Awareness was defined by the presence of explicit memory of any event from the induction of anesthesia to the recovery of consciousness in the postanesthetic care unit (PACU). A final study population of 514 patients was evaluated. None of the answers given by any patient during any of the 3 interviews indicated intraoperative awareness, with the exception of one 54-year-old male patient. Most likely, this potential awareness did not take place during the operation but was caused by inadequate awakening in the PACU.
Therefore, the authors conclude that, with respect to intraoperative awareness, the "Leipzig Fast-Track Concept" with the use of ultra-short-acting opioids should be considered as a safe method of management of patients undergoing a wide variety of cardiac operations.
在直接收治术后恢复室的心脏手术患者中,确定接受快速通道麻醉管理的患者术中知晓并能回忆的发生率。
前瞻性研究。
大学附属心脏中心。
534 例行快速通道麻醉的患者。
作为质量保证计划的一部分,采用结构化访谈过程。
在 8 个月期间,所有快速通道患者均在一所大学医院入组研究。每位患者均由研究人员使用相同的标准问题集在术后 24 小时内进行访谈。术后第 3 或第 4 天以及第 6 或第 7 天进行随访访谈。知晓定义为从麻醉诱导到术后恢复室(PACU)意识恢复期间存在任何事件的明确记忆。最终评估了 514 例患者。在 3 次访谈中的任何一次中,没有任何患者的回答表明存在术中知晓,除了一位 54 岁的男性患者。很可能,这种潜在的意识不是在手术过程中发生的,而是由于 PACU 中的唤醒不足引起的。
因此,作者认为,就术中知晓而言,使用超短效阿片类药物的“莱比锡快速通道概念”应被视为管理接受各种心脏手术患者的安全方法。