Department of Pediatric Neurology and Developmental Medicine, Children's Hospital, University of Tübingen, Germany.
Eur J Paediatr Neurol. 2010 Nov;14(6):474-8. doi: 10.1016/j.ejpn.2010.05.002. Epub 2010 May 26.
Functional MRI is increasingly used to determine the hemispheric dominance for language. This is especially relevant in children who may not be able to comply with the high demands of a Wada test. We here report on two children in which the full extent of language reorganization was only determined when two fMRI tasks were analyzed; in the first case, the results from the second task corroborated the shifted hemispheric dominance seen in the first task. In the second case, the second task showed an opposite hemispheric dominance, suggesting a hemispheric dissociation of language functions. These cases underline the necessity to use more than one fMRI task for the determination of hemispheric dominance, whenever possible. This is particularly relevant in children as unusual patterns of reorganization may be more likely.
功能磁共振成像（fMRI）越来越多地用于确定语言的优势半球。对于那些可能无法满足瓦达测试高要求的儿童来说，这一点尤为重要。我们在这里报告了两个儿童的案例，只有当分析两个 fMRI 任务时，才能确定语言重组的全部范围；在第一个案例中，第二个任务的结果证实了第一个任务中观察到的优势半球转移。在第二个案例中，第二个任务显示出相反的半球优势，提示语言功能的半球分离。这些案例强调了在可能的情况下，使用多个 fMRI 任务来确定优势半球的必要性。对于儿童来说，这一点尤为重要，因为可能更容易出现异常的重组模式。
