College of Urban and Environmental Sciences, Peking University, Beijing 100871, China.
J Chromatogr A. 2010 Jul 16;1217(29):4873-6. doi: 10.1016/j.chroma.2010.04.074. Epub 2010 May 24.
A simple, fast and sensitive liquid chromatography-electrospray tandem mass spectrometry method was established for trace levels of nine haloacetic acids (HAAs) in drinking water. Water samples were removed of residual chlorine by adding L-ascorbic acid, and directly injected after filtered by 0.22 microm membrane. Nine HAAs were separated by liquid chromatography in 7.5 min, and the limits of detection were generally between 0.16 and 0.99 microg/L except for chlorodibromoacetic acid (1.44 microg/L) and tribromoacetic acid (8.87 microg/L). The mean recoveries of nine target compounds in spiked drinking water samples were 80.1-108%, and no apparent signal suppression was observed. Finally, this method was applied to determine HAAs in the tap water samples collected from five waterworks in Shandong, China. Nine HAAs except for monochloroacetic acid, monobromoacetic acid, dibromochloroacetic acid and tribromoacetic acid were detected, and the total concentrations were 7.79-36.5 microg/L. The determination results well met the first stage of the Disinfectants/Disinfection By-Products (D/DBP) Rules established by U.S.EPA and Guidelines for Drinking-water Quality of WHO.
建立了一种用于痕量水中九种卤乙酸（HAAs）的简单、快速、灵敏的液相色谱-电喷雾串联质谱检测方法。水样中加入抗坏血酸以去除余氯，经 0.22μm 膜过滤后直接进样。九种卤乙酸在 7.5 分钟内得到分离，除氯二溴乙酸（1.44μg/L）和三溴乙酸（8.87μg/L）外，其余八种的检出限均在 0.16-0.99μg/L 之间。九种目标化合物在加标饮用水样品中的平均回收率为 80.1%-108%，未观察到明显的信号抑制。最后，该方法应用于测定中国山东五个水厂自来水中的卤乙酸。除一氯乙酸、一溴乙酸、二溴氯乙酸和三溴乙酸外，还检测到其他九种卤乙酸，总浓度为 7.79-36.5μg/L。测定结果符合美国环保署制定的消毒剂/消毒副产物（D/DBP）法规第一阶段标准和世界卫生组织饮用水质量指南的要求。
