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[使用冷冻保存的同种异体移植物修复坐骨神经缺损整形手术后腘窝和髂内侧淋巴结的反应特征]

[Characteristics of the reactions of popliteal and medial iliac lymph nodes after plastic surgery of the sciatic nerve defect using cryopreserved allogeneic transplant].

作者信息

Chaĭkovskiĭ Iu B

出版信息

Arkh Anat Gistol Embriol. 1991 Jan;100(1):24-31.

PMID:2053863
Abstract

Histologically and morphometrically structural transformations in the popliteal and iliac medial lymph nodes have been studied in dogs at plasty of their ischiatic nerve by means of a cryopreserved allotransplant. In one week after the operation in the popliteal and in one month in the iliac nodes appear and then develop further certain reactions in B-dependent areas. In 4-12 weeks after the nerve transplantation certain statistically significant changes are noted in the thymus-dependent zone of the iliac medial lymph nodes. During first two weeks from the beginning of the experiment increase in the relative area of the popliteal lymph nodes sinuses is observed. The transformations described are interpreted as a response of the immune system to the nerve cut, and as a result of it--denervation of the crural tissues, disturbance of their nervous trophic, as well as--to transplantation of the allogeneic nervous trunk. The data obtained are in accordance with results of immunological investigations.

摘要

通过冷冻保存的同种异体移植对犬坐骨神经进行成形术时,对其腘窝和髂内侧淋巴结的组织学和形态计量学结构变化进行了研究。术后一周,腘窝淋巴结出现并随后在B细胞依赖区进一步发展某些反应;术后一个月,髂淋巴结出现并随后发展某些反应。神经移植后4 - 12周,髂内侧淋巴结的胸腺依赖区出现某些具有统计学意义的变化。从实验开始的前两周,观察到腘窝淋巴结窦的相对面积增加。所描述的这些变化被解释为免疫系统对神经切断的反应,以及由此导致的小腿组织去神经支配、其神经营养紊乱,以及同种异体神经干移植的结果。所获得的数据与免疫学研究结果一致。

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