Arogundade R A
Department of Radiodiagnosis, Lagos University Teaching Hospital, Lagos, Nigeria.
Niger Postgrad Med J. 2010 Jun;17(2):168-71.
Brain tumours and head trauma are two pathological entities that may involve the central nervous system to produce similar clinical neurologic signs and symptoms. There has been a long-term debate in the literature on association between these two clinical conditions following observations over time of development of intracranial tumours in individuals who previously sustained head injury. In this teaching centre, there were in succession, two cases of head injury which, at brain CT scanning, turned out to be brain tumours. These findings stimulated the need to review the literature.
To examine the literature for evidence of the role of brain tumour as a factor in development of falls and subsequent head injury and thus raise awareness of their association.
Related literature materials on brain tumours and head injury were reviewed.
Some reports in the medical literature established only weak evidence in support of head injury as an aetiologic agent for brain tumour occurrence; others found no association between them. CT and MRI are useful investigative modalities.
Head trauma may only have caused small and preexisting quiescent tumour to grow as a result of predisposition to fall by musculoskeletal incoordination caused by the tumour itself.
脑肿瘤和头部创伤是两种可能累及中枢神经系统并产生相似临床神经体征和症状的病理实体。长期以来,文献中一直存在关于这两种临床情况之间关联的争论,这是由于对先前遭受头部损伤的个体颅内肿瘤发展情况进行了长期观察。在这个教学中心,相继出现了两例头部损伤病例,经脑部CT扫描发现竟是脑肿瘤。这些发现促使有必要对文献进行回顾。
查阅文献,寻找脑肿瘤作为跌倒及随后头部损伤发生因素的证据,从而提高对它们之间关联的认识。
回顾了有关脑肿瘤和头部损伤的相关文献资料。
医学文献中的一些报告仅提供了薄弱证据支持头部损伤是脑肿瘤发生的病因;其他报告则未发现它们之间存在关联。CT和MRI是有用的检查手段。
头部创伤可能只是由于肿瘤本身导致的肌肉骨骼不协调而使人易于跌倒,从而致使原本存在的小的静止肿瘤生长。