Meşină C, Vasile I, Vîlcea I D, Paşalega M, Pârvănescu H, Calotă F, Georgescu C V, Ghiluşi M, Dumitrescu T, Mirea C, Mogoanţă S, Moraru E
Clinica II Chirurgie, Spit. Clinic Judetean de Urgenţă Craiova, UMF Craiova.
Chirurgia (Bucur). 2010 Mar-Apr;105(2):257-66.
Soft tissue sarcomas are a rare group of cancers compromising 1% of all malignancies and there has been a slight increase in incidence. We present 3 cases of soft tissue sarcomas (the tumors were located to the right axilary region, perianal and dorsale face of the left leg) hospitalized in 2nd Surgical Clinic of Emergency Hospital of Craiova and we discuss the difficulties of diagnosis and treatment. The classification and characterization of soft-tissue sarcomas have evolved as the information supplied by histologic analysis has been supplemented with that provided by immunohistochemical analysis. Surgical resection involving wide margins, with or without radiotherapy, offers the best chance of cure in the absence of metastatic disease. There is little evidence that local recurrence increases the likelihood of metastatic spread, although debate on this point continues. Except for rhabdomyosarcomas and Ewing's sarcomas, the use of adjuvant chemotherapy generally does little to influence the natural history of the disease. In conclusion surgical treatment is mainstay of treatment for soft-tissue sarcomas and is usefull the prompt diagnosis for decrease the risk of local recurrence and metastatic disease.
软组织肉瘤是一类罕见的癌症，占所有恶性肿瘤的1%，其发病率略有上升。我们报告了3例软组织肉瘤病例（肿瘤分别位于右腋窝区域、肛周和左腿背面），这些病例均在克拉约瓦急诊医院第二外科诊所住院治疗，我们还讨论了诊断和治疗的难点。随着组织学分析提供的信息得到免疫组化分析提供的信息的补充，软组织肉瘤的分类和特征也在不断演变。在没有转移性疾病的情况下，采用广泛切缘的手术切除，无论是否联合放疗，都提供了最佳的治愈机会。几乎没有证据表明局部复发会增加转移扩散的可能性，尽管关于这一点的争论仍在继续。除横纹肌肉瘤和尤因肉瘤外，辅助化疗的使用通常对疾病的自然病程影响不大。总之，手术治疗是软组织肉瘤治疗的主要手段，及时诊断对于降低局部复发和转移性疾病的风险很有用。
