3-溴-4,5,6,7-四氢-1,2-苯并异恶唑衍生物的合成及其抗真菌性能
Synthesis and antifungal properties of 3-bromo-4,5,6,7-tetrahydro-1,2-benzoisoxazole derivatives.
作者信息
Napoletano M, Chiarino D, Sala A, Albini E, Pinasi C
机构信息
Laboratori di Ricerca Zambon Group, Milano, Italy.
出版信息
Farmaco. 1991 Jan;46(1):21-31.
PMID:2054039
Abstract
The synthesis of 3-bromo-4,5,6,7-tetrahydro-1,2-benzoisoxazole derivatives and their activity against human pathogen fungi are reported. In particular, compound 3,5-dibromo-6,7-dihydro-1,2-benzoisoxazol-4-(5H)-one showed a broad antifungal spectrum and good fungicidal activity against Trichophyton mentagrophytes.
摘要
报道了3-溴-4,5,6,7-四氢-1,2-苯并异恶唑衍生物的合成及其对人类病原真菌的活性。特别是，化合物3,5-二溴-6,7-二氢-1,2-苯并异恶唑-4-(5H)-酮显示出广谱抗真菌活性，对须癣毛癣菌具有良好的杀菌活性。
Zotero 插件