Chemical burns of the eye with special reference to alkali burns.

Alkali burns of the eye are more severe than acid burns because of the rapid penetration through the cornea and anterior chamber, combining with cell membrane lipids, thereby resulting in disruption of the cells and stromal mucopolysaccharides with concomitant tissue softening. Effective emergency measures must be instituted immediately followed by careful clinical evaluation in order to recognize and treat problems as they arise. We present our experience with 27 patients who sustained corneal lime burns, two of which are discussed in detail. The problem of chemical burns of the eye is reviewed with special emphasis on alkali burns.