Adolescents Unit and Gastrenterology, Hepatology and Nutrition Unit, Pediatrics Department, Braga Hospital, and Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal.
Ital J Pediatr. 2010 Jun 11;36:42. doi: 10.1186/1824-7288-36-42.
We report a case of a 15-year-old boy with autoimmune hepatitis lacking common serologic markers and normal gammaglobulinemia associated with immune thrombocytopenia and family history of psoriasis. He presented to our department with a 4-year history of a cervical posterior lymphadenopathy and recent petechiae. Previous laboratory results 6 months before already showed hepatocellular injury. After exclusion of other causes, the diagnosis of autoimmune hepatitis was made based on clinical grounds, associated immune disorder and histological features of liver biopsy.The authors alert for this atypical presentation of autoimmune hepatitis and associated immune thrombocytopenia.
我们报告了一例 15 岁男孩的病例，该男孩患有自身免疫性肝炎，缺乏常见的血清学标志物且免疫球蛋白正常，伴有免疫性血小板减少症和银屑病家族史。他因 4 年的颈部后淋巴结病和近期瘀点就诊于我科。6 个月前的先前实验室结果已显示肝细胞损伤。排除其他原因后，根据临床、相关免疫紊乱和肝活检的组织学特征，诊断为自身免疫性肝炎。作者提醒注意这种自身免疫性肝炎和相关免疫性血小板减少症的非典型表现。
