Pastor-Navarro T, Beamud-Cortés M, Fornas-Buil E, Moratalla-Charcos L M, Osca-García J M, Gil-Salom M
Hospital Universitario Doctor Peset, Valencia, España.
Actas Urol Esp. 2010 Jul;34(7):592-7.
Investigation in cell therapy and regenerative medicine, mainly developed around stem cell research, is reaching promising results in every medical specialities. There are also being great advances in Urology, despite the difficulties researchers are facing, as complete identification and isolation of human urothelial and prostatic stem cells has not been possible yet, although many groups are close to achieve it.
We performed an electronic research through the Pubmed database, of both original and review publications, with the following search criteria: "stem cells urology", "urothelial stem cells", "bladder stem cells", "prostate stem cells", "urethra stem cells", "cell therapy urology", "tissue engineering urology" y "regenerative medicine urology".
We reviewed 30 articles published up to November 2009, trying to summarize thoroughly the most relevant findings and the last advances in this field, from the first steps to this day.
Despite the great lack of knowledge existing, especially the need for achieving the identification of kidney, urothelium and prostate stem cells, this shouldn't prevent researchers from translating the laboratory results to the clinical work.
主要围绕干细胞研究开展的细胞治疗和再生医学研究，在各个医学专科领域都取得了令人瞩目的成果。尽管研究人员面临诸多困难，但泌尿外科领域也取得了巨大进展，因为目前尚无法完全鉴定和分离出人尿路上皮干细胞和前列腺干细胞，不过许多研究团队已接近实现这一目标。
我们通过PubMed数据库对原始文献和综述进行了电子检索，检索标准如下：“干细胞 泌尿外科”、“尿路上皮干细胞”、“膀胱干细胞”、“前列腺干细胞”、“尿道干细胞”、“细胞治疗 泌尿外科”、“组织工程 泌尿外科”以及“再生医学 泌尿外科”。
我们回顾了截至2009年11月发表的30篇文章，试图全面总结该领域从最初阶段到当前的最相关研究发现和最新进展。
尽管目前存在大量未知，尤其是在鉴定肾、尿路上皮和前列腺干细胞方面仍有需求，但这不应阻碍研究人员将实验室结果转化为临床应用。
