再循环内体的转运。
Transport at the recycling endosome.
机构信息
Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
出版信息
Curr Opin Cell Biol. 2010 Aug;22(4):528-34. doi: 10.1016/j.ceb.2010.05.008. Epub 2010 Jun 11.
Abstract
The recycling endosome (RE) has long been considered as a sub-compartment of the early endosome that recycles internalized cargoes to the plasma membrane. The RE is now appreciated to participate in a more complex set of intracellular itineraries. Key cargo molecules and transport factors that act in these pathways are being identified. These advancements are beginning to reveal complexities in pathways involving the RE, and also suggest ways of further delineating functional domains of this compartment.
摘要
再循环内体（RE）长期以来一直被认为是早期内体的一个亚区室，它将内化的货物再循环到质膜。现在，人们认识到 RE 参与了更复杂的一系列细胞内途径。作用于这些途径的关键货物分子和运输因子正在被鉴定。这些进展开始揭示涉及 RE 的途径的复杂性，并提出了进一步划分该隔室功能域的方法。
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