Deng Jing, Tan Hongzhuan, Yang Tubao, Huang Xin, Zhou Shujin
Department of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha 410078, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 May;35(5):470-5. doi: 10.3969/j.issn.1672-7347.2010.05.011.
To estimate the benefit and cost of increasing the coverage of cervical cancer screening.
Using an eleven year conventional screening data (universal strategy) and a representative population sample (expanding strategy) to analyze the health and economic impact.
The screening coverage for all 30-59 women in Liuyang was increased from 7.20% to 66.67%. Early detection cases were increased from 20 to 45, and life years saved in one screening term increased from 103.46 years to 925.83 years with expanding strategy as compared with the conventional strategy. The incremental cost per life year saved was 6 917.07 Yuan. The benefit/cost ratio was 1.80:1 at the screening coverage of 66.67%, which was higher than that of the conventional strategy (1.40:1). Both strategies were cost-effective.
With various uncertainties and data limitations, expanding screening coverage is more effective than conventional strategy, and more benefit is obtained when the number of early detection cases increases.
评估提高宫颈癌筛查覆盖率的效益和成本。
采用11年的传统筛查数据(普遍策略)和代表性人群样本(扩大策略)来分析健康和经济影响。
浏阳市所有30 - 59岁女性的筛查覆盖率从7.20%提高到66.67%。早期检测病例从20例增加到45例,与传统策略相比,采用扩大策略时一个筛查周期内挽救的生命年数从103.46年增加到925.83年。每挽救一个生命年的增量成本为6917.07元。在筛查覆盖率为66.67%时,效益/成本比为1.80:1,高于传统策略(1.40:1)。两种策略均具有成本效益。
尽管存在各种不确定性和数据限制,但扩大筛查覆盖率比传统策略更有效,且早期检测病例数增加时能获得更多效益。