Lazaar H Ben Gobrane, Aounallah-Skhiri H, Oueslati F, Frikha H, Achour N, Hsairi M
Institut national de la Santé publique, Tunis, Tunisie.
East Mediterr Health J. 2010 Jun;16(6):602-8.
We aimed to identify the most appropriate screening strategy for cervical cancer (periodicity of 3, 5 or 10 years) for Tunisia, taking into consideration the incidence of the disease, costs of screening and economic implications. We simulated follow-up of a fictitious cohort of 1 million women 35-39 years over 30 years. Computation of yearly medical care costs was based on data from medical files of patients diagnosed with cervical cancer in 2004 at the National Institute of Cancer, Tunis. For a 60% coverage level of screening, cervical cancer reduction would be 49.2% for a 3-year periodicity. The reduction would be 40.3% and 33.1% for 5 and 10 years periodicity respectively. Considering cost-effectiveness, 10-year screening gave the lowest annual cost to avoid 1 cervical cancer case.
我们旨在考虑到突尼斯宫颈癌的发病率、筛查成本及经济影响，确定最适合该国的宫颈癌筛查策略（筛查周期为3年、5年或10年）。我们模拟了100万名35至39岁女性在30年中的随访情况。年度医疗费用的计算基于2004年突尼斯国家癌症研究所确诊的宫颈癌患者医疗档案数据。在筛查覆盖率为60%的情况下，筛查周期为3年时宫颈癌减少率为49.2%，筛查周期为5年和10年时减少率分别为40.3%和33.1%。考虑到成本效益，10年筛查周期避免1例宫颈癌病例的年度成本最低。
