Hoevenaar-Blom Marieke P, Wendel-Vos G C W, Spijkerman Annemieke M W, Kromhout Daan, Verschuren W M M
Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Eur J Cardiovasc Prev Rehabil. 2011 Feb;18(1):41-7. doi: 10.1097/HJR.0b013e32833bfc87.
Physical activity is inversely related to cardiovascular diseases. However, the type of activities that contribute most to these beneficial effects remain unclear. For this reason, we investigated self-reported leisure time physical activities in relation to fatal/nonfatal cardiovascular disease incidence.
The Dutch Monitoring Project on Risk Factors for Chronic Diseases Study, carried out between 1993 and 1997, is a prospective cohort study of over 23000 men and women aged 20–65 years from the general Dutch population.
From 1994 till 1997 physical activity was assessed with a questionnaire in 7451 men and 8991 women who were followed for an average of 9.8 years. Cox proportional hazards models were used adjusting for age, sex, other physical activities, smoking, alcohol consumption, and educational level.
Almost the entire study population (97%) was engaged in walking, about 75% in regular cycling, and about half the population in sports or gardening. Cycling [hazard ratio (HR): 0.82, 95% confidence interval (CI): 0.71–0.95] and sports (HR: 0.74, 95% CI: 0.64–0.87) were both inversely related to cardiovascular disease incidence, whereas walking and gardening were not. For sports (P < 0.001), but not for cycling (P = 0.06), we found a dose - response relationship with respect to cardiovascular disease incidence. Engaging in both cycling and sports resulted in an even greater risk reduction (HR: 0.64, 95% CI: 0.52–0.77).
In this relatively active population, types of activities of at least moderate intensity, such as cycling and sports were associated with lower CVD incidence, whereas activities of lower intensity, such as walking and gardening, were not.
身体活动与心血管疾病呈负相关。然而,对这些有益效果贡献最大的活动类型仍不明确。因此,我们调查了自我报告的休闲时间身体活动与致命/非致命心血管疾病发病率的关系。
1993年至1997年开展的荷兰慢性病风险因素监测项目研究,是一项对荷兰普通人群中23000多名20 - 65岁男女进行的前瞻性队列研究。
1994年至1997年,通过问卷调查对7451名男性和8991名女性的身体活动进行了评估,这些人平均随访了9.8年。使用Cox比例风险模型对年龄、性别、其他身体活动、吸烟、饮酒和教育水平进行了调整。
几乎整个研究人群(97%)都有步行活动,约75%有定期骑自行车活动,约一半人群有运动或园艺活动。骑自行车(风险比[HR]:0.82,95%置信区间[CI]:0.71 - 0.95)和运动(HR:0.74,95% CI:0.64 - 0.87)均与心血管疾病发病率呈负相关,而步行和园艺活动则不然。对于运动(P < 0.001),但对于骑自行车(P = 0.06),我们发现与心血管疾病发病率存在剂量 - 反应关系。同时进行骑自行车和运动导致更大程度的风险降低(HR:0.64,95% CI:0.52 - 0.77)。
在这个相对活跃的人群中,至少中等强度的活动类型,如骑自行车和运动,与较低的心血管疾病发病率相关,而较低强度的活动,如步行和园艺活动,则不然。