Hein I M, Huyser C
En Jeugdpsychiater, De Bascule Amsterdam.
Tijdschr Psychiatr. 2010;52(6):417-21.
This article, which was triggered by a case study of a 15-year-old female patient, gives an overview of the literature on the use of olanzapine as an adjunctive treatment for anorexia nervosa in adolescents. On the basis of studies performed so far (two small double-blind placebo-controlled studies, two open-label trials, one retrospective study, a number of case studies that included adolescents, and four series of case studies on adolescents alone), the short-term results of using olanzapine were promising. However, careful monitoring is needed.
本文由一名15岁女性患者的病例研究引发，概述了有关奥氮平作为青少年神经性厌食症辅助治疗药物的文献。根据目前已开展的研究（两项小型双盲安慰剂对照研究、两项开放标签试验、一项回顾性研究、多项纳入青少年的病例研究以及四项仅针对青少年的病例系列研究），使用奥氮平的短期效果颇具前景。然而，仍需进行密切监测。
