Swietokrzyskie Cardiology Centre, Regional District Hospital Department of Cardiology, Kielce, Poland.
Cardiol J. 2010;17(2):189-91.
We describe the case of a 57 year-old woman with NSTE ACS, a history of recurrent and prolonged epistaxis, and low prior cardiovascular risk. Additional findings revealed anemia and an aneurysm in her central nervous system. During her hospital stay, hereditary hemorrhagic telangiectasia (HHT) was diagnosed. After application of two antiplatelet drugs, the patient was scheduled for coronarography, followed by coronary artery bypass grafting. During her hospital stay, only a minor episode of epistaxis was observed. We conclude that anemization due to HTT may significantly accelerate the progress of ischemic heart disease, resulting in acute coronary syndrome. Moreover, coronarography preceded by routine application of two antiplatelet drugs seems not to increase the risk of hemorrhage in HHT patients complicated with myocardial infarction.
我们描述了一位 57 岁女性的病例，她患有 NSTE ACS，有反复发作和长时间的鼻出血病史，且先前的心血管风险较低。其他发现显示她患有贫血和中枢神经系统动脉瘤。在住院期间，诊断出遗传性出血性毛细血管扩张症（HHT）。在应用两种抗血小板药物后，患者接受了冠状动脉造影检查，随后进行了冠状动脉旁路移植术。在住院期间，仅观察到轻微的鼻出血发作。我们得出结论，由于 HHT 引起的贫血可能会显著加速缺血性心脏病的进展，导致急性冠状动脉综合征。此外，在心肌梗死合并 HHT 的患者中，常规应用两种抗血小板药物进行冠状动脉造影似乎不会增加出血风险。
