Sadoh W E, Ibhanesehbor S E, Monguno A M, Gubler D J
Department of Child Health, University of Benin/ University of Benin Teaching Hospital, Benin City, Nigeria.
West Afr J Med. 2010 Mar-Apr;29(2):86-90.
Tracking of blood pressure from childhood to adulthood is well known. It is therefore important to determine predictors of blood pressure as early as at birth.
To determine the association between maternal and neonatal factors on the blood pressure at birth of a group of Nigerian babies.
Consecutive full term neonates delivered in a tertiary centre in Nigeria were recruited for the study. Each newborn's systolic blood pressure (NSBP) was measured within the first four days of life. The mothers' weight, height, body mass index (BMI) and socioeconomic status (SES) were determined while the babies' weight and crown-heel length were measured as well.
Four hundred and seventy-three mother/baby pairs were recruited for the study. The mean NSBP was 69.2 +/- 8.3 mmHG. The birth weight significantly correlated with NSBP,(r = 0.235, p = 0.0001). The NSBP rose an average of 3.61 mmHg per 0.5 kg increase in birth weight. The mean NSBP of babies of mothers with BMI <30 was significantly lower than in babies whose mothers had BMI>30, p=0.031. The mean NSBP of babies from low SES was significantly higher than middle or high SES groups p=0.022.
The study shows that child birth weight is the most significant predictor of newborn systolic blood pressure.
从儿童期到成年期的血压追踪情况已广为人知。因此，尽早在出生时确定血压的预测因素很重要。
确定一组尼日利亚婴儿出生时母亲和新生儿因素与血压之间的关联。
招募在尼日利亚一家三级中心分娩的连续足月新生儿进行研究。在出生后的头四天内测量每个新生儿的收缩压（NSBP）。测定母亲的体重、身高、体重指数（BMI）和社会经济地位（SES），同时也测量婴儿的体重和顶臀长度。
共招募了473对母婴进行研究。平均NSBP为69.2±8.3 mmHg。出生体重与NSBP显著相关（r = 0.235，p = 0.0001）。出生体重每增加0.5 kg，NSBP平均升高3.61 mmHg。BMI<30的母亲所生婴儿的平均NSBP显著低于BMI>30的母亲所生婴儿，p = 0.031。来自低SES的婴儿的平均NSBP显著高于中SES或高SES组，p = 0.022。
该研究表明，出生体重是新生儿收缩压最显著的预测因素。
