Department of Community Health and Psychiatry, University of the West Indies, Mona, Kingston, Jamaica.
Trop Med Int Health. 2010 Aug;15(8):945-54. doi: 10.1111/j.1365-3156.2010.02556.x. Epub 2010 Jun 9.
To determine whether a site-based Priorities for Local AIDS Control Efforts (PLACE) HIV prevention intervention in Kingston, Jamaica increased condom use among persons with new or multiple sex partners.
A total of 147 sites where persons go to meet new sex partners were grouped into 50 geographic clusters and randomized to receive or not receive a multilevel PLACE prevention intervention. Baseline cross-sectional surveys of sites and patrons at sites were conducted in 2005 to determine the nature of social activities at sites to better plan the intervention and to ensure that the two arms of the trial were similar. The intervention was delivered by 50 trained outreach workers between January and June 2006. After the intervention two cross-sectional surveys were conducted to assess the extent of intervention implementation and to estimate the proportion of patrons at sites with recent new or concurrent partnerships and inconsistent condom use.
Characteristics of sites and patrons were similar for most variables at intervention and control sites at both baseline and post-intervention. A total of 1535 patrons (723 men, 812 women) were interviewed at intervention sites and 1324 patrons (661 men, 663 women) at control sites 6-9 months after the intervention. There were no significant differences between intervention and control groups in the proportions of men (37.8% and 31.6%) and women (24.6% and 22.6%) who reported new or multiple relationships in the past year and inconsistent condom use. There was no significant difference in the proportion of men or women showing a condom at interview, having a HIV test in the past 12 months or being exposed to the intervention.
An intent-to-treat analysis did not show any intervention effect. This was probably because of difficulty in implementing the intervention, the extent of patron mixing among sites, the intensity of national education campaigns, delay in conducting the post-intervention survey and evidence of other interventions at some control sites.
确定牙买加金斯敦基于地点的地方艾滋病控制努力重点（PLACE）HIV 预防干预是否增加了有新的或多个性伴侣者的 condom 使用。
将 147 个人们去结识新性伴侣的地点分为 50 个地理群集，并随机分配接受或不接受多层次的 PLACE 预防干预。2005 年在地点和地点顾客进行了基线横断面调查，以确定地点的社会活动性质，从而更好地规划干预，并确保试验的两个部分相似。2006 年 1 月至 6 月，由 50 名经过培训的外展工作人员提供干预。干预后进行了两次横断面调查，以评估干预的实施程度，并估计有最近新的或同时的伙伴关系和 condom 使用不一致的地点顾客的比例。
在基线和干预后，干预和对照组的地点和顾客的特征在大多数变量上相似。在干预地点采访了 1535 名顾客（723 名男性，812 名女性），在对照组地点采访了 1324 名顾客（661 名男性，663 名女性），干预后 6-9 个月。在过去一年中报告新的或多个关系和 condom 使用不一致的男性（37.8%和 31.6%）和女性（24.6%和 22.6%）比例方面，干预组和对照组之间没有显著差异。在采访时展示 condom 的男性或女性比例、过去 12 个月内进行 HIV 检测或接触干预的比例均无显著差异。
意向治疗分析没有显示任何干预效果。这可能是由于难以实施干预、地点之间顾客混合的程度、国家教育运动的强度、延迟进行干预后调查以及一些对照组的其他干预措施的证据。
