Department of Neuroscience, Child and Adolescent Psychiatry, Uppsala University, Uppsala, Sweden.
Acta Paediatr. 2010 Nov;99(11):1724-30. doi: 10.1111/j.1651-2227.2010.01906.x. Epub 2010 Jul 19.
This study aims to investigate the prevalence of somatic symptoms in depressed adolescents and in their healthy peers. A second aim is to investigate the correlation, in the depressed adolescents, between the number of somatic symptoms and severe concurrent symptoms, signs and life events.
The total population of 16-17 year olds - in the city of Uppsala - was screened for depression and then interviewed using a structured interview questionnaire. Depressed subjects and matched controls were identified. A total of 177 pairs were used for pair-wise analyses of somatic symptoms. Severe symptoms, signs and life events were selected for analysing their relation to depression with somatic symptoms.
The adolescents with depressive disorders experienced considerably more somatic symptoms than their healthy controls. The duration and depth of the depression correlated with the number of somatic symptoms. There was a strong correlation between depression with many somatic symptoms and suicidal plans/thoughts, suicidal attempts, disruptive behaviour, as well as multiple stressful relationships.
This study demonstrates that somatic symptoms are common in adolescent depression. Multiple somatic symptoms within depression imply a higher severity in terms of duration, depth and psychiatric comorbidity. The strong correlation with suicidal plans, suicidal attempts and disruptive behaviour is concerning.
本研究旨在调查抑郁青少年和健康同龄人中躯体症状的患病率。第二个目的是调查抑郁青少年中躯体症状的数量与严重并存症状、体征和生活事件之间的相关性。
乌普萨拉市的 16-17 岁青少年全部进行了抑郁筛查，然后使用结构化访谈问卷进行访谈。确定了抑郁患者和匹配的对照组。共对 177 对躯体症状进行了两两分析。选择严重的症状、体征和生活事件来分析它们与伴有躯体症状的抑郁之间的关系。
患有抑郁症的青少年经历了更多的躯体症状，明显多于他们的健康对照组。抑郁的持续时间和严重程度与躯体症状的数量相关。伴有多种躯体症状的抑郁与自杀计划/想法、自杀企图、破坏性行为以及多种紧张关系之间存在很强的相关性。
本研究表明，躯体症状在青少年抑郁中很常见。抑郁中存在多种躯体症状表明在持续时间、深度和精神共病方面更为严重。与自杀计划、自杀企图和破坏性行为之间的强烈相关性令人担忧。
