The Royal Children's Hospital, Parkville, Victoria, Australia.
Australas J Dermatol. 2010 May;51(2):124-7. doi: 10.1111/j.1440-0960.2010.00627.x.
We present seven cases of orofacial granulomatosis occurring in paediatric patients aged 6-16 years. All patients were investigated for Crohn's disease and a strong association was found. All patients were treated with intralesional corticosteroid injections with excellent clinical responses. We review the literature and discuss the epidemiological association between childhood orofacial granulomatosis and Crohn's disease, as well as various treatment options, and propose a treatment protocol that was efficacious and well tolerated in all our patients.
我们报告了 7 例发生在 6-16 岁儿童患者的口腔颌面部肉芽肿病。所有患者均进行了克罗恩病的检查，发现存在很强的关联。所有患者均接受了皮损内皮质类固醇注射治疗，获得了极好的临床反应。我们回顾了文献，讨论了儿童口腔颌面部肉芽肿病与克罗恩病之间的流行病学关联，以及各种治疗选择，并提出了一种在我们所有患者中均有效且耐受良好的治疗方案。
