唇部口面部肉芽肿病：2例组织学和免疫组化分析及病损内皮质激素治疗报告

Orofacial granulomatosis of the lip: a report of 2 cases with histological and immunohistochemical analyses and intralesional corticotherapy.

作者信息

Martini M Z, Galletta V C, Pereira E M, De Sousa S C O M, Lemos C A, Migliari D A

机构信息

Department of Oral Diagnosis, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil.

出版信息

Minerva Stomatol. 2010 Oct;59(10):579-81.

PMID:21048550

Abstract

Orofacial granulomatosis is a generic term applied to manifestations of several diseases including sarcoidosis, Crohn's disease, Melkersson-Rosenthal syndrome, cheilitis granulomatosa of Miescher, tuberculosis and foreign-body reactions. What bonds these diseases together is the presence of noncaseating granulomas. A typical clinical manifestation of orofacial granulomatosis is recurrent labial swellings that eventually persist. This article describes 2 cases of OG diagnosed with the aid of immunohistochemical analysis and successfully treated with intralesional steroids.

摘要

口面部肉芽肿病是一个通用术语，适用于多种疾病的表现，包括结节病、克罗恩病、梅尔克森 - 罗森塔尔综合征、米舍尔唇部肉芽肿性唇炎、结核病和异物反应。将这些疾病联系在一起的是存在非干酪样肉芽肿。口面部肉芽肿病的典型临床表现是反复出现唇部肿胀，最终持续不消。本文描述了2例借助免疫组化分析诊断并经病灶内注射类固醇成功治疗的口面部肉芽肿病病例。