基于毛细管的珠微阵列自动化单核苷酸多态性分型技术
Automated single nucleotide polymorphism typing using bead array in capillary tube.
机构信息
High Technology Research Center of Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado, Saitama 350-0288, Japan.
出版信息
J Biosci Bioeng. 2010 Oct;110(4):505-8. doi: 10.1016/j.jbiosc.2010.05.007. Epub 2010 Jun 12.
PMID:20547337
Abstract
A low-cost and simple on-site technique for genotyping single nucleotide polymorphisms (SNPs) was developed. The technique is based on allele-specific primer PCR and the recently developed bead arrays in a single tip technique. The performance of the method was verified by genotyping four SNPs that correlate with cardiovascular diseases.
摘要
开发了一种低成本、简单的现场单核苷酸多态性（SNP）基因分型技术。该技术基于等位基因特异性引物 PCR 和最近开发的单尖端技术中的珠阵列。该方法的性能通过对与心血管疾病相关的四个 SNP 的基因分型来验证。
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