Shinagawa Shunichiro, Toyota Yasutaka, Matsumoto Teruhisa, Sonobe Naomi, Adachi Hiroyoshi, Mori Takaaki, Ishikawa Tomohisa, Fukuhara Ryuji, Ikeda Manabu
Department of Psychiatry, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Brain Nerve. 2010 Jun;62(6):609-14.
The aim of this study was to use the Rivermead Behavioural Memory Test (RBMT) to evaluate everyday memory impairment among community-dwelling elderly who had normal cognitive function and performed daily activities normally but displayed memory impairments,and to diagnose the condition as either mild cognitive impairment or dementia.
Among the 1,290 community-dwelling elderly persons who participated in the study, 72 subjects scored higher than 24 on the Mini-Mental State Examination (MMSE): these subjects performed daily activities normally, but their family members reported that they showed memory impairments. Fifty-two subjects completed RBMT, Clinical Dementia Rating, and brain computed tomography, and a final diagnosis was established.
The mean standard profile score was 15.1+/-5.0 and mean screening score was 6.4+/-3.0. RBMT score was correlated with the MMSE score. Nine of the subjects were diagnosed with dementia and 26 of them were found to be normal. RBMT achieved 100% sensitivity and specificity with regard to the differentiation of subjects with Alzheimer's disease. However, some subjects were diagnosed with dementia even though their RBMT score was higher than the cut-off score.
RBMT was useful in detecting memory impairments of AD subjects in community-based surveys. However, some subjects were diagnosed with dementia because of the existence of other cognitive impairments among community-dwelling elderly.
本研究旨在使用里弗米德行为记忆测试（RBMT）来评估认知功能正常、日常活动正常但存在记忆障碍的社区老年人的日常记忆损害情况，并将该病症诊断为轻度认知障碍或痴呆症。
在参与研究的1290名社区老年人中，72名受试者在简易精神状态检查表（MMSE）上得分高于24分：这些受试者日常活动正常，但他们的家人报告称他们存在记忆障碍。52名受试者完成了RBMT、临床痴呆评定量表和脑部计算机断层扫描，并得出了最终诊断结果。
平均标准剖面图得分是15.1±5.0，平均筛查得分是6.4±3.0。RBMT得分与MMSE得分相关。其中9名受试者被诊断为痴呆症，26名被认定为正常。在区分阿尔茨海默病患者方面，RBMT的灵敏度和特异性均达到了100%。然而，一些RBMT得分高于临界值的受试者仍被诊断为痴呆症。
在基于社区的调查中，RBMT有助于检测阿尔茨海默病患者的记忆损害情况。然而，由于社区老年人中存在其他认知障碍，一些受试者被诊断为痴呆症。
