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T1期直肠癌经肛门切除或经肛门内镜微创手术后的复发情况。

Recurrences after transanal excision or transanal endoscopic microsurgery of T1 rectal cancer.

作者信息

Hermsen P E A, Nonner J, De Graaf E J R, Doornebosch P G

机构信息

Department of Surgery, Erasmus MC, Rotterdam, The Netherlands.

出版信息

Minerva Chir. 2010 Apr;65(2):213-23.

Abstract

Local excision for T1 rectal cancer is increasingly applied, in a strive to avoid the morbidity associated with radical surgery, despite limited evidence. One of the issues is the high rate of local recurrence following local excision (LE). In this article we focus on this item and review the literature articles concerning local excision and transanal endoscopic microsurgery (TEM), recurrence, and salvage surgery. Local recurrence rates after LE or TEM are unacceptably high. As outcome of this subgroup is limited, future studies should focus on proper tumor selection and adjuvant treatment strategies following salvage surgery.

摘要

尽管证据有限,但为了避免与根治性手术相关的发病率,T1期直肠癌的局部切除术应用越来越广泛。其中一个问题是局部切除(LE)后局部复发率很高。在本文中,我们聚焦于这一问题,并回顾了有关局部切除和经肛门内镜显微手术(TEM)、复发及挽救性手术的文献。LE或TEM后的局部复发率高得令人难以接受。由于该亚组的研究结果有限,未来的研究应聚焦于合适的肿瘤选择以及挽救性手术后的辅助治疗策略。

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