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[枯草芽孢杆菌中核黄素生物合成的操纵子研究。十二。不同基因型细胞中ATP:核黄素-5'-磷酸转移酶和核黄素合成酶含量的测定]

[Operon study of riboflavin biosynthesis in Bacillus subtilis. XII. The determination of the ATP:riboflavin-5'-phosphotransferase and riboflavinsynthetase content in the cells with varying genotypes].

作者信息

Bresler S E, Perumov D A, Glazunov E A, Shevchenko T N, Chernik T P

出版信息

Genetika. 1977;13(5):880-7.

PMID:205483
Abstract

Activities of riboflavinkinase and riboflavinsynthetase were measured in 15 strains of Bacillus subtilis with different genotype. The increased level of riboflavinkinase was observed in strains, resistant to lumiflavin or lumichrome. Specific activity of riboflavinkinase was found to be about 100 times lower than that of riboflavinsynthetase. The regulation of biosynthesis of these enzymes seems to proceed non-coordinately. This phenomenon can be the sequence of the existence of many operators, controlling the flavinogenesis in Bac. subtilis.

摘要

测定了15株不同基因型的枯草芽孢杆菌中核黄素激酶和核黄素合成酶的活性。在对黄素单核苷酸或黄素二核苷酸具有抗性的菌株中观察到核黄素激酶水平升高。发现核黄素激酶的比活性比核黄素合成酶低约100倍。这些酶的生物合成调控似乎是非协调进行的。这种现象可能是存在许多操纵子控制枯草芽孢杆菌中黄素生成的结果。

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