Chernik T P, Bresler S E, Machkovskiĭ V V, Perumov D A
Genetika. 1979 Sep;15(9):1569-77.
Regulatory markers of ribC group were located on the chromosome of Bacillus subtilis by means of genetic transformation. Markers of this group controlling the regulation of riboflavin biosynthesis were mapped between markers of resistance to acriflavin and streptomycin (strC group). The value of cotransfer index between acriflavin-resistance markers and ribC markers was found to be 26--32%. Acriflavin inhibits the riboflavin biosynthesis. The level of inhibition depends on the genotype of riboflavin-producing strains, while the inhibition of the cell growth does not depend on it.
通过遗传转化的方法,将ribC组的调控标记定位在枯草芽孢杆菌的染色体上。该组中控制核黄素生物合成调控的标记位于对吖啶黄素和链霉素抗性(strC组)标记之间。发现吖啶黄素抗性标记与ribC标记之间的共转移指数值为26% - 32%。吖啶黄素抑制核黄素的生物合成。抑制水平取决于核黄素生产菌株的基因型,而对细胞生长的抑制则与之无关。