Frazier O H, Tuzun Egemen, Narin Cuneyt, Cohn William E
Cardiovascular Surgical Research Laboratories, Texas Heart Institute, St. Luke's Episcopal Hospital, Houston, Texas 77030, USA.
Tex Heart Inst J. 2010;37(3):276-9.
Despite recent advances in left ventricular assist device and total artificial heart technologies, these devices are still so large that they pose a significant problem in small patients with refractory heart failure. Excising the left ventricle while preserving the right ventricle--and then replacing the left ventricle with a mechanical pump--has been proposed as an alternative approach to this problem. We conducted a pilot study to evaluate possible surgical techniques and the hemodynamic effects of right ventricle-sparing left ventricular resection and replacement with a continuous-flow rotary blood pump in a healthy bovine model.
尽管最近左心室辅助装置和全人工心脏技术取得了进展，但这些装置仍然非常大，给患有难治性心力衰竭的小患者带来了重大问题。有人提出，切除左心室同时保留右心室，然后用机械泵替代左心室，作为解决这个问题的一种替代方法。我们进行了一项初步研究，以评估在健康牛模型中进行保留右心室的左心室切除并使用连续流旋转血泵替代左心室的可能手术技术和血流动力学效应。
