Son Soo Bin, Heo Young Soo, Shin Won Woong, Oh Tae Seok, Song Hae Jun, Oh Chil Hwan
Department of Dermatology, College of Medicine, Korea University, Seoul, Korea.
Ann Dermatol. 2010 Feb;22(1):91-5. doi: 10.5021/ad.2010.22.1.91. Epub 2010 Feb 28.
Pseudo-inflammatory tumors are also known as plasma cell granuloma, inflammatory pseudo-tumor and inflammatory myofibroblastic tumor, and these tumors are a group of highly variable proliferations of myofibroblastic cells that are associated with a prominent inflammatory infiltrate. This tumor is known to most commonly occur in the lungs, bladder and gastrointestinal system with only a few cases having been reported in the skin. A previously healthy 26-year-old man presented with a 6-year history of an intermittently pruritic lesion on his back. On the histologic examination, there were spindle cells in fascicles and a mixed inflammatory cellular infiltrate of plasma cells and lymphocytes. A diagnosis of inflammatory fibroblastic tumor was made and the nodule was surgically removed. We report here on an additional case of this rare cutaneous entity, and it is probably the first such report from Korea.
假性炎性肿瘤也被称为浆细胞性肉芽肿、炎性假瘤和炎性肌成纤维细胞瘤,这些肿瘤是一组肌成纤维细胞高度可变的增殖性病变,伴有显著的炎性浸润。已知该肿瘤最常发生于肺、膀胱和胃肠道系统,仅有少数皮肤病例报道。一名既往健康的26岁男性,背部出现间歇性瘙痒性病变6年。组织学检查显示,有束状排列的梭形细胞以及浆细胞和淋巴细胞混合性炎性细胞浸润。诊断为炎性纤维母细胞瘤,并手术切除了结节。我们在此报告这一罕见皮肤病变的另一病例,这可能是韩国的首例此类报告。