Fukiage Ken, Fujita Kazutoshi, Toyoda Shingo, Nishimoto Mitsuhisa, Kikuchi Takashi, Chikugo Takaaki, Yoshimura Kazuhiro, Esa Atsunobu, Ito Akihiko, Uemura Hirotsugu
Department of Urology Kindai University Faculty of Medicine Osakasayama Japan.
Department of Urology Kaizuka Municipal Hospital Kaizuka Japan.
IJU Case Rep. 2024 Jan 18;7(2):141-143. doi: 10.1002/iju5.12687. eCollection 2024 Mar.
Inflammatory myofibroblastic tumors are borderline malignant soft tissue tumors primarily affecting the lungs and pelvic organs. This report presents a rare case of an inflammatory myofibroblastic tumor originating from the prostate gland in a young male.
A 20-year-old man developed gross hematuria and dysuria, revealing a prostatic mass. Pathological examination of a biopsy displayed spindle-shaped myofibroblast proliferation and an infiltrate of inflammatory cells, leading to a diagnosis of inflammatory myofibroblastic tumor. Following fertility preservation measures, the patient underwent a robot-assisted laparoscopic total prostatectomy with bilateral nerve sparing, resulting in a postoperative diagnosis of inflammatory myofibroblastic tumor. No recurrence was observed in subsequent imaging, and urinary continence was maintained.
Surgical resection appears effective in managing inflammatory myofibroblastic tumors of the prostate. This case underscores the importance of complete tumor resection due to the significant recurrence risk associated with inflammatory myofibroblastic tumors. Radical total prostatectomy emerges as a potential treatment strategy for prostate originating inflammatory myofibroblastic tumors.
炎性肌纤维母细胞瘤是一种交界性恶性软组织肿瘤,主要累及肺和盆腔器官。本报告介绍了一例罕见的年轻男性起源于前列腺的炎性肌纤维母细胞瘤病例。
一名20岁男性出现肉眼血尿和排尿困难,检查发现前列腺有肿块。活检的病理检查显示梭形肌成纤维细胞增殖和炎性细胞浸润,诊断为炎性肌纤维母细胞瘤。在采取生育保留措施后,患者接受了机器人辅助腹腔镜下双侧神经保留的全前列腺切除术,术后诊断为炎性肌纤维母细胞瘤。后续影像学检查未发现复发,且维持了尿失禁。
手术切除似乎对治疗前列腺炎性肌纤维母细胞瘤有效。该病例强调了由于炎性肌纤维母细胞瘤存在显著的复发风险,完整切除肿瘤的重要性。根治性全前列腺切除术成为起源于前列腺的炎性肌纤维母细胞瘤的一种潜在治疗策略。