Choi Min Jee, Kim Hei Sung, Kim Hyung Ok, Song Kye Yong, Park Young Min
Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ann Dermatol. 2010 May;22(2):219-22. doi: 10.5021/ad.2010.22.2.219. Epub 2010 May 18.
Lymphomatoid keratosis (LK) is considered to be a rare variant of cutaneous lymphoid hyperplasia, with epidermotropism. We herein report a case of LK which developed on the abdomen of an elderly Korean woman. A 60-year-old woman presented with a 10-year history of a pruritic, solitary, brown to black plaque on the abdomen. Histopathologically, the specimen showed hyperkeratosis, parakeratosis, acanthosis and Pautrier's micro-abscess in the epidermis, and a lichenoid infiltration of lymphocytes in the dermis, which expressed both B cell and T cell lineage on the immune-histochemical staining. Based on these clinical and histopathological findings, our case was diagnosed as LK. To our knowledge, this is the first case report of LK in the Korean dermatologic literature.
淋巴瘤样角化病（LK）被认为是皮肤淋巴细胞增生的一种罕见变异型，具有亲表皮性。我们在此报告一例发生在一名老年韩国女性腹部的LK病例。一名60岁女性，腹部有一个瘙痒性、孤立的、棕色至黑色斑块，病史长达10年。组织病理学检查显示，标本表现为表皮角化过度、角化不全、棘层肥厚及帕图里微脓肿，真皮有淋巴细胞苔藓样浸润，免疫组化染色显示其表达B细胞和T细胞谱系。基于这些临床和组织病理学表现，我们的病例被诊断为LK。据我们所知，这是韩国皮肤病学文献中首例LK病例报告。
