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[应激性心肌病]

[Tako-Tsubo cardiomyopathy].

作者信息

Roggenbach J, Roggenbach R, Ehlermann P

机构信息

Klinik für Anaesthesiologie und Intensivmedizin, Klinikum der Universität Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Deutschland.

出版信息

Anaesthesist. 2010 Jul;59(7):636-42. doi: 10.1007/s00101-010-1745-3.

DOI:10.1007/s00101-010-1745-3
PMID:20549172
Abstract

Tako-Tsubo cardiomyopathy (TK) is an acutely appearing myocardial disease leading to impaired cardiac function, which can barely be distinguished clinically from an acute myocardial infarction. It occurs mainly in postmenopausal women and usually has a good prognosis. The pathophysiology of TK still remains to be elucidated but the favoured hypothesis is myocardial damage induced by catecholamine excess. Various acute diseases, emotional stress, surgical procedures and anaesthesia have been described as possible causes for TK. Little is known about the optimal therapy, however, there might be potential differences in the therapy of TK compared to contemporary therapy algorithms for heart failure. Knowledge of TK as a differential diagnosis for acute myocardial infarction is necessary to avoid incorrect treatment.

摘要

应激性心肌病(TK)是一种急性发作的心肌疾病,可导致心功能受损,在临床上很难与急性心肌梗死区分开来。它主要发生在绝经后女性中,通常预后良好。TK的病理生理学仍有待阐明,但最受青睐的假说是儿茶酚胺过量引起的心肌损伤。各种急性疾病、情绪应激、外科手术和麻醉都被描述为TK的可能病因。然而,对于最佳治疗方法知之甚少,与当代心力衰竭治疗算法相比,TK的治疗可能存在潜在差异。了解TK作为急性心肌梗死的鉴别诊断对于避免错误治疗是必要的。

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本文引用的文献

1
Mechanisms of stress (Takotsubo) cardiomyopathy.应激(章鱼壶)心肌病的发病机制。
Nat Rev Cardiol. 2010 Apr;7(4):187-93. doi: 10.1038/nrcardio.2010.16. Epub 2010 Mar 2.
2
Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy.应激(心碎)心肌病的自然病史和广泛的临床表现。
J Am Coll Cardiol. 2010 Jan 26;55(4):333-41. doi: 10.1016/j.jacc.2009.08.057.
3
Cerebral aneurysm surgery in a patient with Brugada syndrome: anesthetic implications and perioperative management.布加综合征患者的脑动脉瘤手术:麻醉影响及围手术期管理
J Neurosurg Anesthesiol. 2010 Jan;22(1):82-3. doi: 10.1097/ANA.0b013e3181bf92ba.
4
Efficacy of levosimendan in Takotsubo-related cardiogenic shock.左西孟旦在应激性心肌病相关心源性休克中的疗效。
Acta Anaesthesiol Scand. 2010 Jan;54(1):119-20. doi: 10.1111/j.1399-6576.2009.02105.x.
5
Clinical characteristics of tako-tsubo cardiomyopathy.应激性心肌病的临床特征。
Am J Cardiol. 2009 Aug 15;104(4):578-82. doi: 10.1016/j.amjcard.2009.04.028. Epub 2009 Jun 18.
6
Preoperative Takotsubo cardiomyopathy identified in the operating room before induction of anesthesia.术前在麻醉诱导前于手术室确诊应激性心肌病。
Anesth Analg. 2010 Mar 1;110(3):712-5. doi: 10.1213/ane.0b013e3181b48594. Epub 2009 Jul 29.
7
Takotsubo cardiomyopathy: a review of the literature.应激性心肌病:文献综述。
Angiology. 2010 Feb;61(2):166-73. doi: 10.1177/0003319709335029. Epub 2009 Jul 21.
8
Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels.应激性心肌病(Takotsubo心肌病)的应激激素和循环生物标志物特征:对B型利钠肽和肌钙蛋白水平临床意义的见解
Heart. 2009 Sep;95(17):1436-41. doi: 10.1136/hrt.2009.170399. Epub 2009 May 24.
9
Stress-induced cardiomyopathy in the perioperative setting.围手术期应激性心肌病
Can J Anaesth. 2009 Jun;56(6):397-401. doi: 10.1007/s12630-009-9085-y.
10
Clinical correlates and prognostic significance of electrocardiographic abnormalities in apical ballooning syndrome (Takotsubo/stress-induced cardiomyopathy).心尖球囊样综合征(Takotsubo综合征/应激性心肌病)中心电图异常的临床相关性及预后意义
Am Heart J. 2009 May;157(5):933-8. doi: 10.1016/j.ahj.2008.12.023.