Roggenbach J, Roggenbach R, Ehlermann P
Klinik für Anaesthesiologie und Intensivmedizin, Klinikum der Universität Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Deutschland.
Anaesthesist. 2010 Jul;59(7):636-42. doi: 10.1007/s00101-010-1745-3.
Tako-Tsubo cardiomyopathy (TK) is an acutely appearing myocardial disease leading to impaired cardiac function, which can barely be distinguished clinically from an acute myocardial infarction. It occurs mainly in postmenopausal women and usually has a good prognosis. The pathophysiology of TK still remains to be elucidated but the favoured hypothesis is myocardial damage induced by catecholamine excess. Various acute diseases, emotional stress, surgical procedures and anaesthesia have been described as possible causes for TK. Little is known about the optimal therapy, however, there might be potential differences in the therapy of TK compared to contemporary therapy algorithms for heart failure. Knowledge of TK as a differential diagnosis for acute myocardial infarction is necessary to avoid incorrect treatment.
应激性心肌病(TK)是一种急性发作的心肌疾病,可导致心功能受损,在临床上很难与急性心肌梗死区分开来。它主要发生在绝经后女性中,通常预后良好。TK的病理生理学仍有待阐明,但最受青睐的假说是儿茶酚胺过量引起的心肌损伤。各种急性疾病、情绪应激、外科手术和麻醉都被描述为TK的可能病因。然而,对于最佳治疗方法知之甚少,与当代心力衰竭治疗算法相比,TK的治疗可能存在潜在差异。了解TK作为急性心肌梗死的鉴别诊断对于避免错误治疗是必要的。