左旋咪唑致可卡因污染后耳闭塞性坏死性血管炎。
Levamisole-induced occlusive necrotizing vasculitis of the ears after use of cocaine contaminated with levamisole.
机构信息
Department of Emergency Medicine, Denver Health and Hospital Authority, 777 Bannock St. MC 0108, Denver, CO, USA.
出版信息
J Med Toxicol. 2011 Mar;7(1):83-4. doi: 10.1007/s13181-010-0097-3.
Abstract
Based on the best available data, approximately 2.1 million Americans use illicit cocaine each month; for the last several months, 30% of that cocaine has been "cut" with a veterinary pharmaceutical, levamisole. Levamisole can cause agranulocytosis, leaving patients susceptible to fulminate and opportunistic infections and also can cause a debilitating cutaneous necrotizing vasculitis. In this manuscript, we describe a case and provide an image of levamisole-induced necrotizing vasculitis of the ears.
摘要
基于现有最佳数据，大约有 210 万美国人每月使用非法可卡因；在过去的几个月里，其中 30%的可卡因被一种兽医药物——左旋咪唑“切割”。左旋咪唑可引起粒细胞缺乏症，使患者易患暴发性和机会性感染，也可引起致残性皮肤坏死性血管炎。在本文中，我们描述了一个病例，并提供了左旋咪唑引起的耳部坏死性血管炎的图像。
相似文献
1
Levamisole-induced occlusive necrotizing vasculitis of the ears after use of cocaine contaminated with levamisole.左旋咪唑致可卡因污染后耳闭塞性坏死性血管炎。
J Med Toxicol. 2011 Mar;7(1):83-4. doi: 10.1007/s13181-010-0097-3.
2
Levamisole-induced vasculitis with ecchymosis and necrosis syndrome from contaminated cocaine.由受污染可卡因引起的伴有瘀斑和坏死综合征的左旋咪唑诱导性血管炎。
BMJ Case Rep. 2012 Nov 21;2012:bcr2012007319. doi: 10.1136/bcr-2012-007319.
3
Small vessel vasculitis associated with cocaine use.与可卡因使用相关的小血管血管炎。
Cutis. 2013 Jan;91(1):21-4.
4
A novel cutaneous vasculitis syndrome induced by levamisole-contaminated cocaine.一种由污染可卡因的左旋咪唑引起的新型皮肤血管炎综合征。
Clin Rheumatol. 2011 Oct;30(10):1385-92. doi: 10.1007/s10067-011-1805-3. Epub 2011 Jun 25.
5
ANCA-positive necrotizing vasculitis and thrombotic vasculopathy induced by levamisole-adulterated cocaine: a distinctive clinicopathologic presentation.由含左旋咪唑的可卡因引起的抗中性粒细胞胞浆抗体（ANCA）阳性坏死性血管炎和血栓性血管病：一种独特的临床病理表现。
J Am Acad Dermatol. 2011 Jul;65(1):e14-6. doi: 10.1016/j.jaad.2010.09.778.
6
Characteristic purpura of the ears, vasculitis, and neutropenia--a potential public health epidemic associated with levamisole-adulterated cocaine.特征性耳部紫癜、血管炎和中性粒细胞减少——与掺假可卡因有关的潜在公共卫生流行。
J Am Acad Dermatol. 2011 Oct;65(4):722-725.e2. doi: 10.1016/j.jaad.2010.08.024. Epub 2011 Jun 11.
7
Levamisole-induced cutaneous vasculitis.左旋咪唑诱发的皮肤血管炎。
Clin Exp Dermatol. 2020 Oct;45(7):935-937. doi: 10.1111/ced.14313. Epub 2020 Jun 29.
8
Levamisole-induced occlusive necrotising vasculitis in cocaine abusers: an unusual cause of skin necrosis and neutropenia.可卡因滥用者中引起闭塞性坏死性血管炎的左旋咪唑：皮肤坏死和中性粒细胞减少的一个不常见病因。
Int Wound J. 2013 Oct;10(5):590-6. doi: 10.1111/j.1742-481X.2012.01027.x. Epub 2012 Jun 21.
9
10
[Thrombotic vasculopathy probably associated with cocaine contaminated with levamisole: report of 2 cases].[可能与被左旋咪唑污染的可卡因相关的血栓性血管病：2例报告]
Rev Med Inst Mex Seguro Soc. 2015 Jan-Feb;53(1):98-101.
引用本文的文献
1
Cocaine-induced vasculitis: is this a new trend?可卡因诱发的血管炎：这是一种新趋势吗？
Open Access Rheumatol. 2013 Oct 3;5:77-80. doi: 10.2147/OARRR.S51524. eCollection 2013.
2
Levamisole/Cocaine Induced Systemic Vasculitis and Immune Complex Glomerulonephritis.左旋咪唑/可卡因诱发的系统性血管炎和免疫复合物性肾小球肾炎。
Case Rep Nephrol. 2015;2015:372413. doi: 10.1155/2015/372413. Epub 2015 Jul 28.
3
Levamisole-adulterated cocaine induced skin necrosis of nose, ears, and extremities: Case report.左旋咪唑掺杂可卡因致鼻、耳及四肢皮肤坏死：病例报告
Allergy Rhinol (Providence). 2014 Jan;5(3):132-6. doi: 10.2500/ar.2014.5.0101.
4
Cocaine induced vasculitis: have we found a culprit?可卡因诱发的血管炎：我们找到病因了吗？
Case Rep Rheumatol. 2012;2012:982361. doi: 10.1155/2012/982361. Epub 2012 Dec 30.
5
Levamisole-induced leukocytoclastic vasculitis and neutropenia in a patient with cocaine use: an extensive case with necrosis of skin, soft tissue, and cartilage.患者使用可卡因致左旋咪唑诱导的白细胞碎裂性血管炎和中性粒细胞减少症：伴有皮肤、软组织和软骨坏死的广泛病例。
Addict Sci Clin Pract. 2012 Sep 24;7(1):19. doi: 10.1186/1940-0640-7-19.
6
Cutaneous vasculopathy associated with levamisole-adulterated cocaine.与左旋咪唑掺杂可卡因相关的皮肤血管病
Clin Med Res. 2013 Feb;11(1):26-30. doi: 10.3121/cmr.2012.1085. Epub 2012 Jun 21.
7
Levamisole-induced occlusive necrotising vasculitis in cocaine abusers: an unusual cause of skin necrosis and neutropenia.可卡因滥用者中引起闭塞性坏死性血管炎的左旋咪唑：皮肤坏死和中性粒细胞减少的一个不常见病因。
Int Wound J. 2013 Oct;10(5):590-6. doi: 10.1111/j.1742-481X.2012.01027.x. Epub 2012 Jun 21.
8
Lupus anticoagulant and ANCA associated thrombotic vasculopathy due to cocaine contaminated with levamisole: a case report and review of the literature.狼疮抗凝物和可卡因污染左旋咪唑所致 ANCA 相关性血栓性血管病：病例报告及文献复习。
J Thromb Thrombolysis. 2012 Jul;34(1):7-10. doi: 10.1007/s11239-012-0711-0.
9
Contaminated cocaine and antineutrophil cytoplasmic antibody-associated disease.被污染的可卡因和抗中性粒细胞胞质抗体相关性疾病。
Clin J Am Soc Nephrol. 2011 Dec;6(12):2799-805. doi: 10.2215/CJN.03440411. Epub 2011 Oct 6.
10
A novel cutaneous vasculitis syndrome induced by levamisole-contaminated cocaine.一种由污染可卡因的左旋咪唑引起的新型皮肤血管炎综合征。
Clin Rheumatol. 2011 Oct;30(10):1385-92. doi: 10.1007/s10067-011-1805-3. Epub 2011 Jun 25.
本文引用的文献
1
Purpura of the ears: a distinctive vasculopathy with circulating autoantibodies complicating long-term treatment with levamisole in children.耳部紫癜：一种伴有循环自身抗体的独特血管病，使儿童左旋咪唑长期治疗复杂化。
Br J Dermatol. 1999 May;140(5):948-51. doi: 10.1046/j.1365-2133.1999.02833.x.
2
Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient.一名儿科患者因左旋咪唑诱导的闭塞性血管炎导致双侧耳垂坏死。
Pediatr Dermatol. 1997 Nov-Dec;14(6):477-9. doi: 10.1111/j.1525-1470.1997.tb00695.x.
Zotero 插件