Faculty of Pharmacy, Area of Toxicology, University of Seville, Profesor García González 2, 41012 Sevilla, Spain.
Environ Toxicol. 2011 Jun;26(3):300-6. doi: 10.1002/tox.20622.
Cyanobacterial toxins have adverse effects on both terrestrial and aquatic plants. Agricultural plants may come in contact with cyanobacterial toxins when surface waters are used for its irrigation. In the present study the effects of MC-LR and cyanobacterial crude extract on three variants of bean by irrigating the seedlings with water containing 5 μg L(-1) MC-LR were assessed. Study of the antioxidant enzymes activities glutathione-S-transferase (GST), peroxidases (POD) and glutathione reductase (GR) was performed in leaves and roots of the seedling exposed to the cyanotoxin compared to a control group and to a group exposed to cyanobacterial crude extract without MCs. Damage of oxidative status was observed in view of the fact that the antioxidant enzymes activities were altered. It is interesting to point out that each variant of bean was affected in a very different way, being GST the most altered enzyme and the B1 the most sensitive variant showing the greatest alterations in the majority of the studied enzymes.
蓝藻毒素对陆生和水生植物都有不良影响。当农业用水取自地表水体时，农作物可能会接触到蓝藻毒素。本研究通过用含有 5μg/L MC-LR 的水灌溉幼苗，评估了 MC-LR 和蓝藻粗提物对三种菜豆品种的影响。与对照组和未含 MCs 的蓝藻粗提取物组相比，研究了暴露于蓝藻毒素的幼苗叶片和根系中的谷胱甘肽 S-转移酶 (GST)、过氧化物酶 (POD) 和谷胱甘肽还原酶 (GR) 等抗氧化酶的活性。鉴于抗氧化酶活性发生了改变，观察到氧化状态受到了损害。有趣的是，每种菜豆品种的反应方式都非常不同，GST 是受影响最大的酶，B1 是最敏感的品种，在大多数研究的酶中表现出最大的变化。
