• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

成功治疗广泛累及神经和皮肤的狨猴阿米巴原虫感染。

Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement.

机构信息

Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.

出版信息

Clin Infect Dis. 2010 Jul 15;51(2):e7-11. doi: 10.1086/653609.

DOI:10.1086/653609
PMID:20550438
Abstract

Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is an uncommon infection for which there is no optimal therapy. We describe a young, female patient who presented with extensive cutaneous and neurological involvement and who recovered after receiving prolonged treatment with miltefosine, fluconazole, and albendazole.

摘要

曼氏利什曼原虫引起的肉芽肿性阿米巴脑炎是一种罕见的感染,目前尚无最佳治疗方法。我们描述了一位年轻女性患者,她表现出广泛的皮肤和神经系统受累,并在接受米替福新、氟康唑和阿苯达唑的长期治疗后康复。

相似文献

1
Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement.成功治疗广泛累及神经和皮肤的狨猴阿米巴原虫感染。
Clin Infect Dis. 2010 Jul 15;51(2):e7-11. doi: 10.1086/653609.
2
Successful treatment of Balamuthia amoebic encephalitis: presentation of 2 cases.巴拉姆希阿米巴脑炎的成功治疗:2例病例报告
Clin Infect Dis. 2003 Nov 15;37(10):1304-12. doi: 10.1086/379020. Epub 2003 Oct 17.
3
Tender ulceronecrotic nodules in a patient with leukemia. Cutaneous acanthamebiasis.一名白血病患者出现的压痛性溃疡坏死结节。皮肤棘阿米巴病。
Arch Dermatol. 2011 Jul;147(7):857-62. doi: 10.1001/archdermatol.2011.162-a.
4
Granulomatous amoebic encephalitis caused by Acanthamoeba amoebae of genotype T2 in a human immunodeficiency virus-negative patient.一名人类免疫缺陷病毒阴性患者中由T2基因型棘阿米巴原虫引起的肉芽肿性阿米巴脑炎。
J Clin Microbiol. 2008 Jan;46(1):338-40. doi: 10.1128/JCM.01177-07. Epub 2007 Nov 14.
5
Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain.用于治疗一例可能由罕见的曼氏巴兰姆希阿米巴菌株引起的肉芽肿性阿米巴脑炎致死病例的米替福新的血脑屏障穿透性评估。
Parasitol Res. 2015 Dec;114(12):4431-9. doi: 10.1007/s00436-015-4684-8. Epub 2015 Sep 2.
6
Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris.由曼氏巴兰姆希阿米巴引起的致命性肉芽肿性阿米巴脑炎。
Med J Aust. 1997 Jul 21;167(2):82-4. doi: 10.5694/j.1326-5377.1997.tb138785.x.
7
Diagnosing Balamuthia mandrillaris encephalitis via next-generation sequencing in a 13-year-old girl.通过下一代测序技术诊断 13 岁女孩中的巴尔通体脑膜脑炎。
Emerg Microbes Infect. 2020 Dec;9(1):1379-1387. doi: 10.1080/22221751.2020.1775130.
8
[Granulomatous amoebic meningoencephalitis by Balamuthia mandrillaris: case report and literature review].[曼氏巴拉姆希阿米巴所致肉芽肿性阿米巴脑膜脑炎:病例报告及文献复习]
Rev Chilena Infectol. 2006 Sep;23(3):237-42. doi: 10.4067/s0716-10182006000300007. Epub 2006 Aug 4.
9
Balamuthia mandrillaris in South America: an emerging potential hidden pathogen in Perú.南美洲的曼氏巴通体:秘鲁一种新出现的潜在隐匿病原体。
Exp Parasitol. 2014 Nov;145 Suppl:S10-9. doi: 10.1016/j.exppara.2014.05.007. Epub 2014 May 21.
10
Balamuthia mandrillaris transmitted through organ transplantation --- Mississippi, 2009.曼氏迭宫绦虫通过器官移植传播---密西西比州,2009 年。
MMWR Morb Mortal Wkly Rep. 2010 Sep 17;59(36):1165-70.

引用本文的文献

1
Discovery of Cyclopentane-Based Phospholipids as Miltefosine Analogs with Superior Potency and Enhanced Selectivity Against .发现基于环戊烷的磷脂作为米替福新类似物,具有更高的效力和对……更强的选择性。
Pharmaceuticals (Basel). 2025 Jun 30;18(7):984. doi: 10.3390/ph18070984.
2
Brainstorm: A Case of Granulomatous Encephalitis.集思广益:一例肉芽肿性脑炎病例
J Assoc Med Microbiol Infect Dis Can. 2024 Jun 12;9(2):113-120. doi: 10.3138/jammi-2023-0036. eCollection 2024 Jun.
3
Encephalitis-causing free-living amoebic infections in children: A rare and fatal disease.
儿童由自由生活阿米巴引起的脑炎感染:一种罕见的致命疾病。
Surg Neurol Int. 2025 May 2;16:166. doi: 10.25259/SNI_65_2025. eCollection 2025.
4
Environmentally derived Balamuthia mandrillaris contains endosymbiotic bacteria.环境来源的曼氏巴通体含有内共生细菌。
Parasitol Res. 2025 Jun 2;124(6):57. doi: 10.1007/s00436-025-08505-0.
5
Cloning of nf-profilin and intercellular interaction with nf-actin in Naegleria fowleri cysts.福氏耐格里阿米巴包囊中nf-肌动蛋白结合蛋白的克隆及其与nf-肌动蛋白的细胞间相互作用
Sci Rep. 2025 Feb 27;15(1):7015. doi: 10.1038/s41598-025-90222-w.
6
Non-granulomatous meningoencephalitis with mimicking a tumor: First confirmed case from Pakistan.非肉芽肿性脑膜脑炎伴肿瘤样表现:巴基斯坦首例确诊病例。
Surg Neurol Int. 2024 Jul 12;15:238. doi: 10.25259/SNI_181_2024. eCollection 2024.
7
Modelling amoebic brain infection caused by Balamuthia mandrillaris using a human cerebral organoid.利用人类大脑类器官模拟由狒狒巴拉姆希阿米巴原虫引起的阿米巴性大脑感染。
PLoS Negl Trop Dis. 2024 Jun 20;18(6):e0012274. doi: 10.1371/journal.pntd.0012274. eCollection 2024 Jun.
8
Amoebicidal effect of chlorine dioxide gas against pathogenic Naegleria fowleri and Acanthamoeba polyphaga.二氧化氯气体对致病性福氏耐格里阿米巴和棘阿米巴的杀阿米巴作用。
Parasitol Res. 2024 Apr 23;123(4):192. doi: 10.1007/s00436-024-08215-z.
9
Challenges and advances in the medical treatment of granulomatous amebic encephalitis.肉芽肿性阿米巴脑炎的医学治疗挑战与进展
Ther Adv Infect Dis. 2024 Feb 2;11:20499361241228340. doi: 10.1177/20499361241228340. eCollection 2024 Jan-Dec.
10
Pathogenic free-living amoebic encephalitis from 48 cases in China: A systematic review.中国48例致病性自由生活阿米巴脑炎的系统评价。
Front Neurol. 2023 Feb 9;14:1100785. doi: 10.3389/fneur.2023.1100785. eCollection 2023.