翠雀中的化学成分及其生物活性。
Chemical constituents from Delphinium chrysotrichum and their biological activity.
机构信息
Department of Applied Chemistry, Xi'an University of Technology, Xi'an 710054, PR China.
出版信息
Fitoterapia. 2010 Oct;81(7):929-31. doi: 10.1016/j.fitote.2010.06.008. Epub 2010 Jun 13.
A new diterpene alkaloid named delphatisine C (1) has been isolated from aerial parts of Delphinium chrysotrichum along with three known norditerpenoid alkaloids delpheline (2), delbrunine (3), and delectinine (4). Their structures were characterized on the basis of their spectral data. All of them were determined by SRB assay for their cytotoxicity, and compound (1) showed significant cytotoxic activities (IC(50)=2.36 μmol/L) against the A549 cell line.
从翠雀属植物（Delphinium chrysotrichum）的地上部分分离得到一种新的二萜生物碱，命名为 delphatisine C（1），同时还分离得到三种已知的北美黄连碱（norditerpenoid alkaloids）：delpheline（2）、delbrunine（3）和 delectinine（4）。基于其光谱数据对它们的结构进行了表征。所有化合物均通过 SRB 测定法进行了细胞毒性测试，化合物 1 对 A549 细胞系显示出显著的细胞毒性活性（IC50=2.36 μmol/L）。
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