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阿片类成瘾者中多种物质使用与精神疾病诊断的聚类分析

Clustering of multiple substance use and psychiatric diagnoses in opiate addicts.

作者信息

Strain E C, Brooner R K, Bigelow G E

机构信息

Department of Psychiatry, Johns Hopkins Hospital, Francis Scott Key Medical Center, Baltimore, MD 21224.

出版信息

Drug Alcohol Depend. 1991 Mar;27(2):127-34. doi: 10.1016/0376-8716(91)90031-s.

DOI:10.1016/0376-8716(91)90031-s
PMID:2055161
Abstract

Using a standardized psychiatric interview, the prevalence of and interrelationships among various substance use diagnoses and non-substance use psychiatric diagnoses were examined in a population of opiate addicts (n = 66) enrolled in methadone maintenance treatment. Multiple substance use disorders were found in these patients, and more substance use disorders were found in those patients with, versus without, a non-substance use psychiatric diagnosis. Certain substance use disorders were found to cluster. These results suggest that opiate addicts should be evaluated for multiple substance use disorders as well as for non-substance use disorders, and that certain subpopulations may be at increased risk for multiple substance use disorders.

摘要

采用标准化的精神病学访谈,对66名接受美沙酮维持治疗的阿片类成瘾者进行了研究,以调查各种物质使用诊断与非物质使用精神病诊断之间的患病率及相互关系。这些患者中存在多种物质使用障碍,与无非物质使用精神病诊断的患者相比,有此类诊断的患者存在更多物质使用障碍。某些物质使用障碍被发现存在聚集现象。这些结果表明,应对阿片类成瘾者进行多种物质使用障碍以及非物质使用障碍的评估,且某些亚群可能有更高的多种物质使用障碍风险。

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