Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.
Clin Cardiol. 2010 Jun;33(6):E73-80. doi: 10.1002/clc.20627.
The objectives of this study were to examine the type and frequency of symptoms in patients hospitalized with acute heart failure (HF) as well as the relationship between symptom patterns and patient characteristics, treatment practices, and hospital outcomes in patients hospitalized with decompensated HF.
The study sample consisted of 4537 residents of the Worcester, MA metropolitan area hospitalized for decompensated HF at 11 greater Worcester medical centers in 1995 and 2000.
The average age of the study sample was 76 years; the majority (57%) were women, and three-quarters of our patient population had been previously diagnosed with HF. Dyspnea (93%) was the most frequent complaint reported by patients followed by the presence of peripheral edema (70%), cough (51%), orthopnea (37%), and chest pain/discomfort (30%). Patients reporting few cardiac symptoms were less likely to be treated with effective cardiac therapies during hospitalization than patients with multiple cardiac signs and symptoms and experienced higher hospital (9.7% vs. 7.7%) as well as 30-day (17.1% vs. 10.2%) death rates (P < 0.05).
The results of this study in residents of a large New England community suggest that patients with fewer reported symptoms of decompensated HF were less likely to receive effective cardiac treatments and had worse short-term outcomes. Reasons for these differences in treatment practices and short-term outcomes need to be elucidated and attention directed to these high-risk patients.
本研究旨在探讨因失代偿性心力衰竭住院患者的症状类型和频率,以及这些症状模式与患者特征、治疗实践和住院结局之间的关系。
本研究的样本包括 1995 年至 2000 年在马萨诸塞州伍斯特市的 11 家大伍斯特医疗中心因失代偿性心力衰竭住院的 4537 名居民。
研究样本的平均年龄为 76 岁;大多数(57%)为女性,我们的患者群体中有四分之三的人以前被诊断为心力衰竭。呼吸困难(93%)是患者最常报告的症状,其次是外周水肿(70%)、咳嗽(51%)、端坐呼吸(37%)和胸痛/不适(30%)。报告心脏症状较少的患者在住院期间接受有效心脏治疗的可能性低于有多种心脏体征和症状的患者,且住院(9.7%比 7.7%)和 30 天(17.1%比 10.2%)死亡率更高(P < 0.05)。
这项在新英格兰地区一个大型社区居民中的研究结果表明,报告的失代偿性心力衰竭症状较少的患者接受有效心脏治疗的可能性较低,且短期预后较差。需要阐明这些治疗实践和短期结局差异的原因,并关注这些高危患者。