Chirillo F, Ramondo A, Razzolini R, Isabella G, Martini M, Andriolo L, Rampazzo C, Chioin R, Della Volta S
Servizio di Emodinamica, Cattedra di Cardiologia, Università degli Studi di Padova.
G Ital Cardiol. 1991 Jan;21(1):33-9.
In order to evaluate the short and mid-term results of percutaneous aortic balloon valvuloplasty, 40 consecutive elderly patients with symptomatic severe calcific aortic stenosis, underwent the procedure consecutively, with follow-up by clinical evaluation and Doppler echocardiography. Over a mean follow-up period of 11.2 months there were 5 deaths, and 12 patients underwent subsequent aortic valve replacement. Doppler echocardiography revealed an increase in aortic valve area from 0.62 +/- 0.20 cm2 to 0.91 +/- 0.23 cm2 after the procedure, but there was a significant trend toward restenosis by 12 months follow-up in 23 of 32 patients (72%). Restenosis was accompanied by symptomatic deterioration in 18 of 23 patients (78%). Although balloon valvuloplasty may often improve haemodynamics and relieve symptoms, these benefits seem to be short-lived in most cases. Restenosis has a high rate of occurrence. Aortic balloon valvuloplasty should be reserved for truly inoperable cases and for haemodynamically-unstable patients, who may later undergo surgery.
为评估经皮主动脉球囊瓣膜成形术的短期和中期结果，40例有症状的重度钙化性主动脉瓣狭窄老年患者连续接受了该手术，并通过临床评估和多普勒超声心动图进行随访。在平均11.2个月的随访期内，有5例死亡，12例患者随后接受了主动脉瓣置换术。多普勒超声心动图显示术后主动脉瓣面积从0.62±0.20平方厘米增加到0.91±0.23平方厘米，但在32例患者中的23例（72%）随访至12个月时有明显的再狭窄趋势。23例患者中有18例（78%）再狭窄伴有症状恶化。尽管球囊瓣膜成形术通常可改善血流动力学并缓解症状，但在大多数情况下这些益处似乎是短暂的。再狭窄发生率很高。主动脉球囊瓣膜成形术应仅用于真正无法手术的病例以及血流动力学不稳定的患者，这些患者随后可能接受手术。
