Vianelli N, Sermasi G, D'Alessandro R, Zucchelli P, Belardinelli A R, Catani L, Belmonte M M, Cascione M L, Gugliotta L
Istituto di Ematologia L. e A. Seràgnoli, Università, Bologna, Italy.
Haematologica. 1991 Jan-Feb;76(1):72-4.
We report on the cases of two women with acute thrombotic thrombocytopenic purpura (TTP) whose clinical courses were characterized by the onset of a coma state. Prompt commencement of plasma-exchange (PE) treatment led to complete hematological and neurological remission, which can still be observed without any maintenance therapy. No CNS abnormalities were observed in either patient using brain CT and NMR scans.
我们报告了两名患有急性血栓性血小板减少性紫癜(TTP)的女性病例,她们的临床病程以昏迷状态发作为特征。及时开始血浆置换(PE)治疗导致血液学和神经学完全缓解,且在没有任何维持治疗的情况下仍可观察到这种缓解。使用脑部CT和核磁共振扫描未在任何一名患者中观察到中枢神经系统异常。