非酒精性脂肪性肝病作为儿童肥胖的一种合并症。
Nonalcoholic fatty liver disease as a comorbidity of childhood obesity.
作者信息
Barshop Nicole J, Francis Cameron S, Schwimmer Jeffrey B, Lavine Joel E
机构信息
Department of Pediatrics, University of California, San Diego, California, CA 92103, USA, Tel.: +1 619 543 7544, ,
出版信息
Ped Health. 2009 Jun 1;3(3):271-281. doi: 10.2217/phe.09.21.
Abstract
Childhood obesity is a worldwide health problem associated with an increase in the prevalence and severity of comorbid conditions including nonalcoholic fatty liver disease (NAFLD). The increasing number of children with NAFLD presents a major public health concern. This review focuses on the recent advancements in the understanding of the epidemiology, diagnosis, histology, pathogenesis and treatment of pediatric NAFLD and highlights ongoing challenges and unmet needs in the area.
摘要
儿童肥胖是一个全球性的健康问题，与包括非酒精性脂肪性肝病（NAFLD）在内的合并症的患病率和严重程度增加有关。患有NAFLD的儿童数量不断增加，这是一个重大的公共卫生问题。本综述重点关注儿童NAFLD在流行病学、诊断、组织学、发病机制和治疗方面的最新进展，并强调该领域目前面临的挑战和未满足的需求。
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