Dental Services Alfred Health Melbourne, Victoria, Australia.
Haemophilia. 2011 Jan;17(1):e185-8. doi: 10.1111/j.1365-2516.2010.02346.x.
In oral surgery, patients with inherited bleeding disorders have historically had factor cover where possible. Factor support is expensive, time consuming to administer and places the patient at a potential risk of complications of therapy. A protocol employing rigorous local measures and minimal factor replacement was used to obtain haemostasis following simple and complex oral surgery on 50 consecutive patients with inherited bleeding disorders, referred to the Alfred Health Dental Unit from the Ronald Sawers Haemophilia Centre, Alfred Health, Melbourne. Excellent haemostasis was achieved using standardized local measures of 5% tranexamic acid solution, surgicel and monocryl sutures. Oral surgery may be considered safe to perform in patients with inherited bleeding disorders using minimal factor support and meticulous local haemostatic measures.
在口腔外科中,患有遗传性出血性疾病的患者在可能的情况下一直接受因子覆盖治疗。因子支持既昂贵又费时,并且会使患者面临治疗并发症的潜在风险。在墨尔本阿尔弗雷德健康罗纳德·索尔斯血友病中心转诊到阿尔弗雷德健康牙科病房的 50 名连续遗传性出血性疾病患者中,我们采用了一种严格的局部措施和最低因子替代的方案,以在进行简单和复杂的口腔手术后实现止血。使用 5%氨甲环酸溶液、Surgicel 和单丝缝线等标准化局部措施可实现出色的止血效果。在使用最低因子支持和细致的局部止血措施的情况下,口腔外科手术可以被认为对患有遗传性出血性疾病的患者是安全的。