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Recent advances in neuroblastoma.

作者信息

Maris John M

机构信息

Center for Childhood Cancer Research, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, and Abramson Family Cancer Research Institute, Philadelphia, PA 19104-4318, USA.

出版信息

N Engl J Med. 2010 Jun 10;362(23):2202-11. doi: 10.1056/NEJMra0804577.

DOI:10.1056/NEJMra0804577
PMID:20558371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3306838/
Abstract
摘要

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Cochrane Database Syst Rev. 2015 Oct 5;2015(10):CD006301. doi: 10.1002/14651858.CD006301.pub4.
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Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study.Hu14.18-IL2 治疗复发/难治性神经母细胞瘤的抗肿瘤活性:一项儿童肿瘤协作组(COG)的 II 期研究。
J Clin Oncol. 2010 Nov 20;28(33):4969-75. doi: 10.1200/JCO.2009.27.8861. Epub 2010 Oct 4.
2
Phase II randomized comparison of topotecan plus cyclophosphamide versus topotecan alone in children with recurrent or refractory neuroblastoma: a Children's Oncology Group study.拓扑替康联合环磷酰胺与拓扑替康单药治疗复发或难治性神经母细胞瘤患儿的 II 期随机对照研究:一项儿童肿瘤学组研究。
J Clin Oncol. 2010 Aug 20;28(24):3808-15. doi: 10.1200/JCO.2009.27.5016. Epub 2010 Jul 26.
3
Mycn对青春期乳腺发育至关重要,并促进由Bcl11b维持的静止干细胞的激活。
Cells. 2025 Aug 12;14(16):1239. doi: 10.3390/cells14161239.
4
GD2-targeting CAR T cells in high-risk neuroblastoma: a phase 1/2 trial.针对高危神经母细胞瘤的GD2靶向嵌合抗原受体T细胞:一项1/2期试验。
Nat Med. 2025 Aug 21. doi: 10.1038/s41591-025-03874-6.
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Design, synthesis, and biological evaluation of 5-chlorine-2-amino-pyrimidine derivatives as potent PLK4 inhibitors.5-氯-2-氨基嘧啶衍生物作为有效的PLK4抑制剂的设计、合成及生物学评价
RSC Med Chem. 2025 Aug 14. doi: 10.1039/d5md00435g.
6
The baseline F-FDG PET/CT imaging features in pediatric patients with congenital neuroblastoma.先天性神经母细胞瘤患儿的基线F-FDG PET/CT影像特征。
BMC Med Imaging. 2025 Aug 14;25(1):330. doi: 10.1186/s12880-025-01863-2.
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AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression.AXL酪氨酸激酶抑制剂TP-0903通过靶向miR-335-3p/DKK1表达诱导活性氧触发神经母细胞瘤细胞凋亡。
Cell Death Discov. 2025 Aug 13;11(1):378. doi: 10.1038/s41420-025-02681-9.
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Degradation of IRF6 by TRIM59 in tumor cells triggers PGM1-mediated glycolysis to regulate cell proliferation in neuroblastoma.TRIM59在肿瘤细胞中对IRF6的降解触发了PGM1介导的糖酵解,以调节神经母细胞瘤中的细胞增殖。
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Transl Cancer Res. 2025 Jul 30;14(7):4058-4070. doi: 10.21037/tcr-2024-2472. Epub 2025 Jul 14.
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Transl Cancer Res. 2025 Jul 30;14(7):3920-3929. doi: 10.21037/tcr-2025-569. Epub 2025 Jul 4.
Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP).
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Pediatr Blood Cancer. 2010 Jul 15;55(1):26-34. doi: 10.1002/pbc.22430.
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Common variations in BARD1 influence susceptibility to high-risk neuroblastoma.常见的 BARD1 变异影响高危神经母细胞瘤的易感性。
Nat Genet. 2009 Jun;41(6):718-23. doi: 10.1038/ng.374. Epub 2009 May 3.
7
Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force.通过免疫细胞学和定量逆转录聚合酶链反应(QRT-PCR)灵敏检测骨髓、血液和干细胞制剂中微小神经母细胞瘤细胞的共识标准:国际神经母细胞瘤风险组工作组的建议
Br J Cancer. 2009 May 19;100(10):1627-37. doi: 10.1038/sj.bjc.6605029. Epub 2009 Apr 28.
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Overall genomic pattern is a predictor of outcome in neuroblastoma.整体基因组模式是神经母细胞瘤预后的一个预测指标。
J Clin Oncol. 2009 Mar 1;27(7):1026-33. doi: 10.1200/JCO.2008.16.0630. Epub 2009 Jan 26.
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The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report.国际神经母细胞瘤风险组(INRG)分类系统:INRG 工作组报告。
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The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report.国际神经母细胞瘤风险组(INRG)分期系统:一份INRG特别工作组报告。
J Clin Oncol. 2009 Jan 10;27(2):298-303. doi: 10.1200/JCO.2008.16.6876. Epub 2008 Dec 1.