Department of Psychosomatics and Health Behaviour, Norwegian Institute of Public Health, Box 4404 Nydalen, 0403 Oslo, Norway.
J Pediatr Psychol. 2011 Mar;36(2):179-87. doi: 10.1093/jpepsy/jsq054. Epub 2010 Jun 17.
To examine the relationship between the severity of infants' congenital heart defects (CHD) and their mothers' symptoms of depression and anxiety from pregnancy to 18 months postpartum.
Mothers of infants with mild, moderate, or severe CHD (n=162) and mothers (n=44,400) within the Norwegian Mother and Child Cohort Study were assessed with an eight-item short version (SCL-8) of the Hopkins Symptom Checklist-25 at the 30th week of gestation and at 6 and 18 months postpartum.
Only the postpartum mental health trajectory of mothers of infants with severe CHD deviated from the mental health trajectory of the cohort at 6 and 18 months postpartum, showing significantly elevated levels of depression and anxiety symptoms.
The results elucidate the relationship between infants' CHD severity and maternal symptoms of depression and anxiety, possibly identifying a specifically vulnerable patient dyad in need of postoperative interventions.
探讨从妊娠到产后 18 个月，婴儿先天性心脏病（CHD）严重程度与母亲抑郁和焦虑症状之间的关系。
对 162 例轻度、中度或重度 CHD 婴儿的母亲（病例组）和挪威母婴队列研究中的 44400 名母亲（对照组）在妊娠第 30 周、产后 6 个月和 18 个月时采用 Hopkins 症状清单-25 的 8 项简短版本（SCL-8）进行评估。
只有重度 CHD 婴儿的母亲产后心理健康轨迹在产后 6 个月和 18 个月时与队列的心理健康轨迹偏离，表现出明显更高水平的抑郁和焦虑症状。
研究结果阐明了婴儿 CHD 严重程度与母亲抑郁和焦虑症状之间的关系，可能确定了需要术后干预的特定脆弱患者对子。
