Department of Otorhinolaryngology Head and Neck Surgery, Zonguldak Karaelmas University School of Medicine, Zonguldak, Turkey.
Acta Otorhinolaryngol Ital. 2010 Apr;30(2):115-7.
Distinguishing keratoacanthoma from well-differentiated squamous-cell carcinoma is often difficult on account of the clinical and histopathological similarities between them. Since the outcome of treatment depends on identifying the correct diagnosis and having the correct treatment on time, it is essential to differentiate keratoacanthoma and squamous-cell carcinoma as soon and accurately as possible. A paradigmatic case is herein reported. An 85 year-old female underwent total parotidectomy and ipsilateral neck dissection due to the squamous-cell carcinoma of the parotid gland. The investigations, in order to determine whether the tumour was a metastatic or a primary one, led to a misdiagnosis. A prior skin lesion, which was excised over her left cheek one year ago in another clinic, was diagnosed as keratoacanthoma. However, the histopathological revision of the specimen revealed that the lesion was in fact a squamous-cell carcinoma. Thus the parotid tumour was accepted as metastatic squamous-cell carcinoma rather than primary squamous-cell carcinoma.
鉴别角化棘皮瘤与分化良好的鳞状细胞癌通常很困难，因为它们在临床和组织病理学上有相似之处。由于治疗结果取决于确定正确的诊断并及时进行正确的治疗，因此尽快准确地区分角化棘皮瘤和鳞状细胞癌至关重要。本文报告了一个典型病例。一位 85 岁女性因腮腺鳞状细胞癌接受了腮腺全切除术和同侧颈淋巴结清扫术。为了确定肿瘤是转移瘤还是原发性肿瘤而进行的检查导致了误诊。一年前在另一家诊所切除的她左脸颊上的一个先前的皮肤病变被诊断为角化棘皮瘤。然而，对标本的组织病理学复查显示，病变实际上是鳞状细胞癌。因此，腮腺肿瘤被认为是转移性鳞状细胞癌而不是原发性鳞状细胞癌。
