Department of Epidemiology, University of Alabama at Birmingham, 1530 3rd Avenue South, RPHB 517, Birmingham, AL 35294-0022, USA.
Osteoporos Int. 2011 Apr;22(4):1263-74. doi: 10.1007/s00198-010-1300-8. Epub 2010 Jun 18.
Medicare claims data were used to investigate associations between history of previous fractures, chronic conditions, and demographic characteristics and occurrence of fractures at six anatomic sites. The study confirmed previously established associations for hip and spine fractures and identified several new associations of interest for nonhip, nonspine fractures.
This study investigates the associations of a history of fracture, comorbid chronic conditions, and demographic characteristics with incident fractures among Medicare beneficiaries. The majority of fracture incidence studies have focused on the hip and on white females. This study examines a greater variety of fracture sites and more population subgroups than prior studies.
We used Medicare claims data to examine the incidence of fracture at six anatomic sites in a random 5% sample of Medicare beneficiaries during the time period 2000 through 2005.
For each type of incident fracture, women had a higher rate than men, and there was a positive association with age and an inverse association with income. Whites had a higher rate than nonwhites. Rates were lowest among African-Americans for all sites except ankle and tibia/fibula, which were lowest among Asian-Americans. Rates of hip and spine fracture were highest in the South, and fractures of other sites were highest in the Northeast. Fall-related conditions and depressive illnesses were associated with each type of incident fracture, conditions treated with glucocorticoids with hip and spine fractures and diabetes with ankle and humerus fractures. Histories of hip and spine fractures were associated positively with each site of incident fracture except ankle; histories of nonhip, nonspine fractures were associated with most types of incident fracture.
This study confirmed previously established associations for hip and spine fractures and identified several new associations of interest for nonhip, nonspine fractures.
利用医疗保险索赔数据,调查既往骨折史、慢性疾病以及人口统计学特征与 6 个解剖部位骨折发生的关联。本研究证实了髋部和脊柱骨折的先前确立的关联,并确定了非髋部、非脊柱骨折的几个新的关联。
本研究调查了既往骨折史、合并的慢性疾病以及人口统计学特征与医疗保险受益人的骨折发生之间的关联。大多数骨折发生率研究都集中在髋部和白人女性。本研究比以往研究检查了更多的骨折部位和更多的人群亚组。
我们使用医疗保险索赔数据,在 2000 年至 2005 年期间,检查了 6 个解剖部位的随机 5%的医疗保险受益人的骨折发生率。
对于每种类型的新发骨折,女性的发生率均高于男性,且与年龄呈正相关,与收入呈负相关。白人的发生率高于非白人。除了脚踝和胫骨/腓骨外,所有部位的骨折发生率均最低,而在亚洲裔美国人中,脚踝和胫骨/腓骨的骨折发生率最低。髋部和脊柱骨折的发生率在南部最高,其他部位的骨折发生率在东北部最高。与跌倒相关的疾病和抑郁疾病与每种新发骨折相关,使用糖皮质激素治疗的疾病与髋部和脊柱骨折相关,糖尿病与脚踝和肱部骨折相关。既往的髋部和脊柱骨折史与除脚踝以外的所有新发骨折部位均呈正相关;既往非髋部、非脊柱骨折史与大多数新发骨折类型相关。
本研究证实了髋部和脊柱骨折的先前确立的关联,并确定了非髋部、非脊柱骨折的几个新的关联。