Department of Urology, Asklepios Hospital Barmbek, Ruebenkamp 220, 22291, Hamburg, Germany.
World J Urol. 2010 Aug;28(4):519-24. doi: 10.1007/s00345-010-0572-0. Epub 2010 Jun 19.
Nephron sparing surgery has been established as a standard treatment for renal masses smaller than 4 cm in diameter. The benefit of nephron sparing surgery may be hampered by new types of complications. In particular, postoperative gross hematuria due to the formation of renal artery pseudoaneurysm (RAP) can lead to clinical significant hemorrhage. We retrospectively investigated the occurrence of postoperative RAP in our own consecutive series of open/laparoscopic partial nephrectomies requiring transarterial angioembolization.
Open partial nephrectomy (OPN) was performed in 289 patients, and laparoscopic partial nephrectomy (LPN) in 40 patients. Six patients (1.82%) developed postoperative clinical symptomatic, persistent gross hematuria from RAP. Patient files were evaluated for preoperative, operative and postoperative data.
First symptom presentation was observed at a median of 12.5 days (range 6-36) after surgery. Symptoms were flank pain, gross hematuria, dizziness/syncope and/or fever. Median postoperative blood transfusion rate was 3 units (range 0-8). RAP was proven with angiography in all patients. RAP was sufficiently occluded in all patients by using microcoils in a supraselective approach. Median follow-up was 23 months (range 10-37) without any episodes of hemorrhage/flank pain in each patient.
RAP is a rare, but typical complication after partial nephrectomy. The clinical symptoms present with delay. Angiography identifies the origin of the bleeding and provides successful minimally invasive treatment.
肾部分切除术已被确立为治疗直径小于 4 厘米的肾肿瘤的标准治疗方法。保肾手术的益处可能会受到新类型并发症的阻碍。特别是,由于肾动脉假性动脉瘤(RAP)的形成而导致的术后肉眼血尿可能导致临床明显出血。我们回顾性地调查了我们自己连续的开放性/腹腔镜部分肾切除术患者中需要动脉血管栓塞术的术后 RAP 的发生情况。
289 例患者行开放性部分肾切除术(OPN),40 例患者行腹腔镜部分肾切除术(LPN)。6 名患者(1.82%)发生术后临床症状性、持续性 RAP 肉眼血尿。评估患者的术前、术中和术后数据。
首次出现症状的时间中位数为术后 12.5 天(范围 6-36)。症状包括腰痛、肉眼血尿、头晕/晕厥和/或发热。中位术后输血率为 3 单位(范围 0-8)。所有患者均通过血管造影证实为 RAP。所有患者均采用微线圈超选择性方法充分闭塞 RAP。中位随访时间为 23 个月(范围 10-37),每位患者均无出血/腰痛发作。
RAP 是肾部分切除术后罕见但典型的并发症。临床症状出现延迟。血管造影可确定出血的来源,并提供成功的微创治疗。